Title: To study common cause of UTI in Female patients coming to Hospital with Special focus to restrain Antibiotic resistance

Authors: Dr Mohini Nainani, Dr Manish Pokra, Dr Yogendra Kumar Tiwari

 DOI:  https://dx.doi.org/10.18535/jmscr/v4i12.131

Abstract

Urinary tract infections (UTIs) are conditions frequently complained by women both in the general population and in the hospital setting. Indeed it has been estimated that one woman out of three will experience at least an episode of UTI during lifetime. Urinary tract infections (UTIs) are one of the most frequent clinical bacterial infections in women, accounting for nearly 25% of all infections. Around 50–60% of women will develop UTIs in their lifetimes. Resistance in Gram-negative bacteria has been increasing, particularly over the last 6 years. This is mainly due to the spread of strains producing extended-spectrum β-lactamases (ESBLs) such as CTX-M enzymes or AmpC β-lactamases. Many of the isolates producing these enzymes are also resistant to trimethoprim, quinolones and aminoglycosides, often due to plasmid co-expression of other resistance mechanisms. CTX-M-producing Escherichia coli often occurs in the community and as E. coli is one of the commonest organisms causing urinary tract infections (UTIs) the choice of agents to treat these infections is diminishing. This study aimed to find bacterial profile of urinary tract infection (UTI) in female patients. This is a hospital based retrospective study conducted at Government Medical College, Jhalawar over a period of September 2015 to November 2016. Clean catch mid-stream urine samples from 500 clinically suspected cases of urinary tract infections were processed as per standard procedures. Among the 500 patients, 88 were found to be culture positive.

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Corresponding Author

Dr Manish Pokra