Abstract

Eyelid histology comprises of various structures that gives rise to wide spectrum of pathologies.  Eyelid lesions require surgical treatment mostly; hence a correct preoperative provisional diagnosis is required. Histopathological examination of the excised specimen with confirmation of clinical diagnosis given plays an enormous role in treating eyelid lesions so as to improve patients care. We studied 25 cases of eyelid lesions retrospectively over a period of a year. We came across epidermal cyst as a most common lesion occurring in eyelid followed by capillary hemangioma, dermal nevus and molluscum contagiosum. Uncommon lesions that were diagnosed were pilomatricoma, tumoral calcinosis, cysticercosis which completely differed from the clinical diagnosis offered. In conclusion, each and every excised specimen should not be considered as waste material and always be (without exception) sent for the histopathological examination for correct diagnosis and further management.

Keywords- eyelid lesions, common and uncommon, histopathology

1.      Mihaela- Cristiana Coroi, Elena Ro Ca, Gabriela Mu Iu, T. Coroi, Marinela Bonta. Eyelid tumors: histopathological and clinical study performed in County Hospital of Oradea between 2000.2007. Romanian Journal of Morphology and Embryology 2010, 51(1):111.115

2.      Chauhan S, Shah S, Solanki P et al. Accuracy of clinical diagnosis of eyelid lesion in a medical college in Gujarat. Int’l J Res Med 2013; 2: 114-7

3.      Ophthalmic Pathology Service. Available from: http//www.smbs.buffalo.edu/ophthalmology/clinical Services/pathology_fed.html. Accessed January, 2012

4.      Calonje E, Brenn T, Lazar A, Mckee PH. Cutaneous cysts. In : Mckee’s Pathology of the Skin with clinical correlation. Volume 2. Calonje E, Brenn T, Lazar A, Mckee PH, editors. Fourth edition. Elsevier Saunders; 2012.pp 1571-4

5.      Pudasaini S,  Kansakar I, Prasad KBR, Rauniyar SK. A histopathological study of ophthalmic lesions. Nepal Med Coll J 2013; 15(1): 78-80

6.      Bastola P, Koirala  S , Pokhrel  G , Ghimire P , Adhikari RK.  A clinico-histopathological study of orbital and ocular lesions; a multicenter study. Journal of Chitwan Medical College 2013; 3(4): 40-44

7.      Calonje E, Brenn T, Lazar A, Mckee PH. Connective tissue tumors. In : Mckee’s Pathology of the Skin with clinical correlation. Volume 2. Calonje E, Brenn T, Lazar A, Mckee PH, editors. Fourth edition. Elsevier Saunders; 2012.pp 1714-5

8.      Ramya B S,Dayananda S B, Chinmayee J T, Raghupathi A R. Tumours of the Eyelid- A Histopathological Study of 86 Cases in a Tertiary Hospital. International Journal of Scientific and Research Publications, 2014;4(11):1-5

9.      Pe’er J. Pathology of eyelid tumors. Indian J Ophthalmol. 2016 Mar; 64(3): 177–190.

10.  Zuzur B, Bastian B, Calonje E. Melanocytic nevi.  In : Mckee’s Pathology of the Skin with clinical correlation. Volume 2. Calonje E, Brenn T, Lazar A, Mckee PH, editors. Fourth edition. Elsevier Saunders; 2012.pp 1156-63

11.  Malherbe A, Chenantais J(1880) Note sur L'epitheliome calcife des glandes sebacees. Prog Med (Paris) 8:826–837. Google Scholar

12.  Mathen L C, Olver J M. A large rapidly growing pilomatrixoma on a lower eyelid. Br J Ophthalmol 2000;84:1203

13.  Calonje E, Brenn T, Lazar A, Mckee PH. Tumors of hair follicles. In : Mckee’s Pathology of the Skin with clinical correlation. Volume 2. Calonje E, Brenn T, Lazar A, Mckee PH, editors. Fourth edition. Elsevier Saunders; 2012.pp 1460-63

14.  Llamas-Velasco M, Eguren C, Santiago D, et al. Calcinosis cutis and Sjogren's syndrome. Lupus 2010;19:762-4

15.  Schornack MM, Siemsen DW, Bradley EA, Salomao DR , Lee HB. Ocular manifestations of molluscum contagiosum. Clin Exp Optom 2006; 89: 6: 390–393

16.  Grayson W. Infectious diseases of the skin. In : Mckee’s Pathology of the Skin with clinical correlation. Volume 2. Calonje E, Brenn T, Lazar A, Mckee PH, editors. Fourth edition. Elsevier Saunders; 2012. 760-895

17.  Al-faky Y H. Epidemiology of benign eyelid lesions in patients presenting to a teaching hospital. Saudi Journal of Ophthalmology (2012) 26, 211–216

18.  Foyaca-Sibat H, Salazar-Campos M, Iban ez-Valde s L. Cysticercosis of the Extraocular Muscles. Our Experience And Review Of The Medical Literature. The Internet Journal of Neurology. 2012;14(1).

19.  Khalil MF, abdelrazik ST. Malignant eyelid lesions: histopathological types and degree of tissue invasion at the time of presentation. J Egypt Ophthalmol Soc 2015;108:52-6