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Category: Volume 11 Issue 10 October 2023
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Title: Giant Chorioangioma in a Patient with 36 Weeks of Pregnancy: A Case Report

Authors: Bandana Mehrotra, Sanjay Mehrotra, Ashok Kumar Kapoor, Mithlesh Bhargava, Divya Arora, Rahul Kumar Pandey6, Supriya Mehrotra

 DOI: https://dx.doi.org/10.18535/jmscr/v11i10.04

Abstract

Present report relates to a 40-year-old patient with 36 weeks of pregnancy and non-trophoblastic benign placental neoplasm chorioangioma (placental hemangioma). The incidence of chorioangioma has been described as 0.5 to 1.0 % of all pregnancies. Tumors may be >4 cm in diameter; such tumors are called giant tumors. Smaller tumors are generally asymptomatic. However, clinically-significant chorioangioma occur less frequently; incidence varying from 1 in 3500 to 1 in 9000 pregnancies. Giant chorioangiomas are very rare tumors; only a few cases have been reported. Feto-maternal complications like fetal growth retardation, anemia and hydrops may develop in a patient with chorioangioma. Further, fetal loss may be as high as ~ 40 %. Increased incidence of chorioangiomas may occur at high-altitude pregnancies, suggesting role of hypobaric hypoxia in pathogenesis of chorioangioma.

Keywords: Well-circumscribed benign placental neoplasm.

References

  1. Clarke I: Account of a tumor found in substance of the human placenta. Philos Trans 1798 ; 88: 361-8.10.1098 / rstl.1798 : 0016
  2. Sun X, Zhao H, HaO I, Lu L, GuY: Clinicopathological characteristics of placental chorioangioma: a clinicopathological study of 77 cases. Ann Diagn Pathol 2022 ; 57 : 10
  3. Theresia E, Nurdiati DS , Widodo I. Giant placental chorangioma : The first case report in Indonesia . Human Pathology: case reports 2021 ; 23: 200472
  4. Kataria N, Singh A, Bedi PK. Giant placental chorangioma : A rare case report. J Clin Diag Res 2016; 10 (4) ED3 - ED4
  5. Lez C, Fures Z, Hrgovic S, Bellina J, Fajdie K, Muenstedt. Chorioangioma Rare Tumors 2010 ; 2 (4): 67
  6. Kesrouani Ak, Safi J, El Haji MA. Rapid evolution of placental chorioangioma: natural progression and outcome. J Ultras Med 2013; 32: 545-7
  7. Hongwei Ma , Zilling L , Jie R. Placental Chorioangioma and pregnancy outcome : A ten year retrospective study in a tertiary referral centre. Res Square 2023; p1-15
  8. Schenone CV, Rodriguez A, Duncan J, Steffensen T, John B, Obican S. Giant placental chorioangioma and severe ductal arch constriction : A case report with a favorable outcome. Cureus 2023 ; 15 (4) e38209
  9. Shiraga A, Ohsuga T, Kawasaki K, Mogami H, Minamiguchi S. A case of placental multiple giant chorangioma leading to neonatal death from fetal hydrops. Case report. Perinat Med 2023:12 (1) 2022008
  10. Dong T, Luo Q. Pregnancy complications and adverse outcomes in placental chorioangiomas-a retrospective cohort analysis. J Matern Fetal Neonatal Med 2018; 1: 5
  11. Zou J, Ding W; Chen Q, Bai X, Li B. Safety of vaginal delivery in women with placental chorioangiomas diagnosed by prenatal ultrasound: A retrospective cohort study. Medicine (Baltimore) 2022; 101 (29): e 29672

Corresponding Author

Dr. Ashok Kumar Kapoor

RML Mehrotra Pathology Pvt. Ltd. B-171, Nirala Nagar, Lucknow- 22602, Uttar Pradesh, India