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Category: Volume 10 Issue 10 October 2022
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Title: Severe myalgia may develop in COVID-19 virus infection: A Case Report

Authors: Bandana Mehrotra, Vasundhara Sharma, Ruchi Shukla, Ashok Kumar Kapoor, Supriya Mehrotra, Rajesh Srivastava, Hari Shyam

 DOI: https://dx.doi.org/10.18535/jmscr/v10i10.04

Abstract

Present case relates to the results of SARS CoV-2 RT-PCR tests which were done in a family. Nasopharyngeal samples were collected from both the parents and from their son. The patient was a 77 years old male. He complained of severe myalgia involving calf, gluteal and abdominal muscles for several days. Later, he developed mild fever. Nasopharyngeal swab was collected on fifth day of the illness and coronavirus RT-PCR test was done. The patient was SARS CoV-2 RT PCR positive. His son was aged 48 years. He complained of hyperpyrexia; coronavirus RT-PCR was also positive. Wife of the patient was RT-PCR negative for SARS CoV-2. Both patient and their son were treated with Paracetamol 650 mg BD, Flavipiravir 400 mg/day and vitamin D 60,000 units/week. Both patient and his son recovered within 7 days.

Keywords: myalgia, RT-PCR, atypical presentation, coronavirus.

References

  1. Abobaker A, Raba AA, Alzwi A. Extrapulmonaty and atypical clinical presentations of COVID-19. J Med Virol 2020; 92:2458-64.
  2. Wang D, Hu B, Hu C, Liu X, Zhu F, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel Coronavirus-infected pneumonia in Wuhan, China. JAMA 2020,323:1061-9.
  3. Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS. Post acute COVID-19 syndrome. Nature Med 2021; 27:601-15.
  4. Joob B, Wiwanitkit V. Atypical presentation of COVID- 19. Am J Emer  med 2021: 39; 237.
  5. Muacevic A , Alder J, R Zhang, Shan KS, Minalyam A, Sullivan Co: A rare Presentation of coronavirus disease 2019 (COVID -19) induced viral myositis with rhabdomyolysis. Cureus 2020;12:e8074.
  6. Saud A, Naveen R, Aggarwal R, Gupta Latika. COVID 19 and myositis : What we know sa far. Curr Rheumatol Rep 2021;23:63.
  7. Guan W, Ni Z, Hu Y, Liang w, Ou C,He J etal. Clinical characteristic s of coronavirus disease 2019 in China. N Eng J Med 2020,382:1708-20.
  8. Saleh NY, Aboelghar HM, Salem SS, Ibrahem RA, Khalil FO, Abdelgawad AS. The severity and atypical presentations of COVID-19 infection in pediatrics. BMC pediatrics 2021; 21: 144.
  9. Hays AP, Armbrustmachar VW, skeletal muscle. In ‘pathology’ Rubin ER, Farber JL (editors), Lippincott-Ravan, Philadelphia (publishers) p1414-1440,1999.
  10. Gan JM. Kho J. Akhunbay-Fudge M, Choo HM, Wright M. Batt F etal. Atypical presentation of COVID-19  in hospitalised  older  Ir  J Med Sci 2021; 190: 409-74.
  11. Huang C, wang Y, Li X, Ren L, Zhao J, Hu Y etal. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet 2020, 395: 497-506.
  12. Vorman DC. Fever in the elderly. Clin Infect Dis 2020; 3:148-51.
  13. Oppenheim JJ, Ruscetti Cytokines. In Parslow TG, slites DP, Terr AI, Inbodem JB eds. ‘Medical immunology’ 10thed. New York Lange medical books/ McGraw-Hill publishing division 2001, p148-166.
  14. Marshall-Gradisnik S, Eaton-Fitch N. Understanding myalgic encephalomyelitis. Science 2022; 377:6611.

Corresponding Author

Dr Ashok Kumar Kapoor