Title: Development of Bioerodable PDO (Polydioxanone) Plate for Nasal Septum Deviation under Controlled Environment

Authors: Minocha Dr. Pramod Kumar, Kothwala Deveshkumar Mahendralal, Shaikh Amirhamzah Mahmadiqbal

 DOI: https://dx.doi.org/10.18535/jmscr/v10i3.29

Abstract

A bioabsorbable plate is a flexible polydioxanone polymer plate. PDO is a synthetic, absorbable monofilament suture manufactured in a controlled environment from paradioxanone polymer. In rhinoplasty and septal surgery, a resorbable PDO plate is connected to the nasal septal cartilage to assess its mechanical stability as the cartilage fragment heals. In this circumstance, the PDS plate can help support the healing cartilage, allowing for adequate repair without compromising the contour or stability of the nose. Septorhinoplasty is the most common procedure for reshaping the nose with bioerodable plates. Bioabsorbable plate is made using a solvent casting technology, making it cost-effective, robust, easy to use, and with a long shelf life. Cartilage grafts are frequently used in rhinoplasty and septal surgery. The use of an absorbable scaffold material to support the reimplanted cartilage during healing can improve the outcome if the cartilage is thin or deviated.

Keywords: Bioabsorbable, nasal septal cartilage, polydioxanone and controlled environment.

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Corresponding Author

Kothwala Deveshkumar Mahendralal

Meril Life Sciences Pvt. Ltd., Bilakhia House, Survey No. 135/139, Muktanand Marg, Chala, Vapi, Dist - Valsad - 396191, Gujarat, India