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Category: Volume 10 Issue 02 February 2022
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Title: Prevalance of H. Pylori Infection in Patients of Cirrhosis of Liver with Its Etiological Correlation

Authors: Dr Mahendra Pratap Singh, Dr A K Yadav, Dr Balvir Singh, Dr A Gautam

 DOI: https://dx.doi.org/10.18535/jmscr/v10i2.14

Abstract

Objective: Prevalance of h. pylori infection in patients of cirrhosis of liver with its etiological correlation

Method: 100 diagnosed cases (newly and previously diagnosed cases) of chronic liver disease admitted in Medicine Department at S.N. Medical College, Agra were included in the study.  The duration of study was 18 months (during the period from June 2015 to January 2017).A thorough history, physical examination and Investigations were done, patients were categorized in different CHILD PUGH Grades and also categorized according to the different grades of esophageal varices and hepatic encephalopathy.

Result: In our study, 100 patients of chronic liver disease were enrolled, out of which 65 patients were male and 35 were female. Most of the patients were in the 41-50 years age group. The most common presenting complains of the patients in our study was ascites (62%) followed by hepatic encepahalopathy (46%) and malena (43%). Among the 100 patients, the most common cause of cirrhosis in our study was alcohol abuse (42%), followed by Hepatitis B (32%) and Hepatitis C (22%). In 4 patients, no obvious cause of cirrhosis could be identified and they were labelled as idiopathic.

Conclusion: All the patients of liver cirrhosis should be evaluated at the earliest for the presence of H pylori infection. The early detection and consequent eradication of H pylori infection may reduce the severity of complications like bleeding esophageal varices, portal gastropathy and hepatic encephalopathy.

Keywords: liver cirrhosis , H pylori, Child Pugh grade, Esophageal varices, Hepatic encephalopathy.

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Corresponding Author

Dr Amit Kumar Yadav

Consultant General Medicine, District Hospital Orai Jalaun Uttar Pradesh, Uttar Pradesh, INDIA