Title: Study on Serum Magnesium Levels in Acute Myocardial Infarction

Authors: Dr Ganta Aneesha, Dr M. Madhusudhan Babu, Dr K. Sudheer, Dr B. Ashok Babu

 DOI: https://dx.doi.org/10.18535/jmscr/v9i12.09

Abstract

Introduction

  • Magnesium has been implicated in the pathogenesis of Acute Myocardial infarction and its complications like arrhythmias.
  • Magnesium ions are considered essential for the maintenance of the functional integrity of the myocardium.
  • Myocardial magnesium concentration in patients with sudden death due to ischemic heart disease was found to be very low. It has been pointed out that magnesium has a vital role in ventricular fibrillation, which causes sudden death in IHD.
  • The coronary vasospasm resulting from magnesium deficiency has been suggested as another important factor in the sudden death in IHD.
  • Magnesium deficiency was also postulated to have role in the genesis of atheromatous plaques in that it leads to hyperlipidemia.

Aims and Objectives

  • To know the relation between level of serum magnesium and arrhythmias in patients with acute myocardial infarction who are presenting within 12 hours of onset of symptoms.

References

  1. Burch GE, Gibs TD. Importance of magnesium deficiency in cardiovascular disease. American Heart Journal. 1977; 94: 649.
  2. Gaetano AL, Stefano C, domenico C et al. Coronary Blood Flow & Myocardial Ischemia. Chapter-46. In: Hurst’s The Heart. 11th edition. McGraw Hill, New York. 2004: p. 11531172.
  3. Grubbs R, Maguire M. Magnesium as a regulatory cation: Criteria and Evaluation. Magnesium. 1987; 6: 113.
  4. Hodegekinson A, Marshall D, Nordin B. Vitamin D and magnesium absorption in man. Clin Science. 1979; 57: 121.

Corresponding Author

Dr Ganta Aneesha

Great Eastern Medical School and Hospital, Srikakulam, India