Title: Comparative in-vitro anthelmintic activity of various parts of Ficus Carica linn
Authors: Sudheshna Loka, Rajyalaxmi Masula, Prakashamani Guntuku
DOI: https://dx.doi.org/10.18535/jmscr/v9i11.25
Abstract
Many commonly available plants like Leonatisleptiifolia, various species of Ficus like Ficus benghalensis, Ficus religiosa etc showed potent anthelmintic activity. The present study was aimed to compare the potencies of various parts of Ficus carica against earth worms as they anatomically resemble the round worms which cause helmenthiasis. Methanolic extract of leaves, stems and fruits of Ficus carica were compared for their in-vitro anthelmintic activity in order to determine the potencies of them. Results revealed that exposure of worms to leaf extract of F.carica takes 2-3 hr to cause paralysis and death of worms with various concentrations of (20,30,40 mcg/ml). The stem extract of F.carica shows almost equal effect with 3hrs of exposure. While the methanolic fruit extract of F.carica is effective at more than 3 hrs of exposure. The results were compared with mebendazole as a positive control and normal saline as a negative control. Mebendazole shows 100% effective on exposure, while worms exposed to normal saline were still alive even after 3hrs of exposure.
Keywords: Ficus benghalensis, helmenthiasis, Mebendazole, earth worms.
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