Title: A Case Series of Neuromyelitis Optica Spectrum Disorders

Authors: Kosuru Sham Charan Naidu, Dr K. Sudheer, Dr M. Madhu Sudhan Babu

 DOI: https://dx.doi.org/10.18535/jmscr/v9i11.20

Abstract

Aim of the Study

To Evaluate and Analyze Cases of Neuromyelitis Optica Spectrum Disorders Presenting to our Hospital, Great Eastern Medical School and Hospital, Srikakulam, Andhra Pradesh.

Materials and Methods

The study was conducted in Great Eastern Medical School and Hospital , Srikakulam, Andhra Pradesh, in the period of 1 year from

September 2019 to August 2020.

All the cases diagnosed to have NMO / NMO SPECTRUM DISORDER were included in the study.

Evaluated clinically and underwent following investigations:

  1. Bio-chemical: complete blood counts, blood sugar, liver and renal function tests
  2. Chest x-ray
  3. ECG
  • Radio imaging - MRI BRAIN/SPINE
  • Serologic work up(NMO- IgG, HIV, HSV, HBsAg)
  • Lumbar puncture and CSF analysis,
  • Evoked potentials (selected patients)
  • Rheumatologic work up(ANA, RA, Anti-Ro/SSA)

References

  1. Wingerchuk D. Neuromyelitis optica. Int MS J. 2006; 13:42-50.
  2. Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology. 2006; 66:1485-89.
  3. Papeix C, Vidal JS, de Seze J, et al. Immunosuppressive therapy is more effective than interferon in neuromyelitis optica. MS. 2007;13(2):256-9.
  4. Wingerchuk DM, Lennon VA, Lucchinetti CF, Pittock SJ, Weinshenker BG. The spectrum of neuromyelitis optica. Lancet Neurol. 2007;6: 805-815.
  5. Jarius S, Wildemann B. AQP4 antibodies in neuromyelitis optica: diagnostic and pathogenetic relevance. Nat Rev Neurol. 2010;6(7):383-92.

Corresponding Author

Kosuru Sham Charan Naidu

Great Eastern Medical School & Hospital,

Srikakulam, Andhra Pradesh, India