Title: Correlation of Gallbladder Volume to Autonomic Neuropathy in Diabetics
Authors: Dr Patimalla Visala Bhavishya, Dr M .Madhusudhana Babu, MD, DM., Dr K. Sudheer, MD
DOI: https://dx.doi.org/10.18535/jmscr/v9i11.19
Abstract
Introduction
- Diabetes mellitus is most common endocrine disorder in humans characterized by chronic hyperglycemia due to defects in insulin secretion, insulin action or both
- Prevalence of diabetes in adults in India is around8.9%
- Complications of diabetes can be divided into acute & chronic complications
- Acute complications include diabetic ketoacidosis, non ketotic hyperosmolar state, hypoglycemia.
- Chronic complications can be divided into microvascular & macrovascular complication
- Microvascular complications include eye disease (retinopathy, macularedema, cataracts), neuropathy (sensory & motor, autonomic), nephropathy
- Macrovascular complications include coronary artery disease, peripheral artery disease, cerebrovascular disease
- Diabetes is the commonest cause of autonomic peripheral A broad spectrum of symptoms affecting cardiovascular, gastrointestinal, urogenital, thermoregulatory, sudomotor & pupillomotor function canoccur
- Gall bladder involvement in diabetic autonomic neuropathy occurs in form of increased gall bladder volume & impaired gall bladder contraction
- Vagal parasympathetic fibers maintain gall bladder tone & influence it’s emptying
- Hence gall bladder dysfunction may occur in autonomic neuropathy
- Due to impaired contraction, stasis occurs and results in gall stone formation
- Therefore gall bladder function should be routinely evaluated in diabetic patients
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