Title: Clinical Profile and Outcomes of Patients Admitted with COVID-19 Infection –Report from a Tertiary Hospital

Authors: Harharpreet Kaur, Manpreet Singh, Kiranjit Kaur, Arvinder Kaur, Randhir Singh, Nehal Patel

 DOI: https://dx.doi.org/10.18535/jmscr/v9i1.37

Abstract

Introduction: Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptoms may be mild which do not need hospital admission. However some patients progress to acute respiratory failure, Adult Respiratory Syndrome (ARDS)/sepsis and require intensive care. There is paucity of data regarding the clinical course of the disease.

Aims and Objectives: To study the clinicodemographic characteristics, associated comorbid conditions and outcomes of COVID 19 patients admitted in a tertiary hospital.

Methods: 185 consecutive patients with confirmed diagnosis of  COVID-19 who were admitted from September 2020 to 31st December 2020 in a tertiary hospital were studied .Only patients with moderate and severe disease were admitted. Rests were advised home quarantine. They were given medical treatment as per Indian guidelines and besides the patient profile their clinical course, oxygen requirement and need for ventilator support and outcomes were studied.

Results: Age ranged from 30-86 years. 62% of  patients were between the age of 51-70 years.68.1% patients were males and 31.9% were females.91.4%patients were admitted with shortness of breath (SOB).Other complaints included fever (10.3%) and cough(18.4%) .68% of the subjects had associated comorbid conditions. Diabetics constituted 49.2% and hypertensives 41.1%of these cases.59% of patients were stabilised on low flow oxygen/without oxygen, 8% required high flow oxygen, 29%needed non invasive ventilation and 3%had to be mechanically ventilated. 57% of patients who required noninvasive ventilation were diabetics. Significantly higher comorbidity was present among patients with severe disease as compared to those with moderately severe disease. (Pearson chi2 (1)=22.9781Pr =0.000). 83% of all admitted patients recoveredcompletely.70%cases who received non invasive ventilation recovered and had no residual complication.5% were referred or left the hospital. The hospital stay ranged from 1 to 36 days. Mortality was 12%.3 patients who expired reported very late and were referred from other centres.

Conclusion: The patients who were admitted with COVID-19 were elderly with a male predominance. Comorbiditywas significantly associated with severe disease. Recovery rate is good with early and aggressive ICU care.

Keywords: COVID-19, Patient profile; Comorbidities, Severe Disease; Outcomes.

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Corresponding Author

Dr Harharpreet Kaur

Professor Medicine, MM Medical College, Kumarhatti, Distt. Solan, Himachal Pradesh, India