Title: Study on Correlation between High Sensitivity C-Reactive Protein Levels and Left Ventricular Function in Patients with Acute Coronary Syndrome
Authors: Dr Aman Deep Goel, Dr Bhupinder Singh, Dr Tarsem Pal Singh
DOI: https://dx.doi.org/10.18535/jmscr/v8i4.19
Abstract
Introduction: Present work was aimed to study the correlation of hs-CRP with left ventricular function in patients of NSTEMI, STEMI and unstable angina. This study was carried out in 120 patients of acute coronary syndrome, presenting to Guru Nanak Dev Hospital attached to Government Medical College, Amritsar.
Material and Methods: Present work is a prospective observational study to determine correlation between plasma hs-CRP levels and outcome in patients with acute coronary syndrome. The data was collected from the patients and recorded in a prepared Case Report Form. Demographic details, medical history, information on exercise, diet, substance use, and hospitalization details was collected. After relevant history and thorough clinical examination, height, weight and BMI were measured. Hs-CRP was measured in patients and echocardiography was performed.
Results: In the present study, the data showcases the relationship between hs- CRP and various echocardiographic parameters in patients with acute coronary syndrome. Observations of the present study shows the correlation between the mean hs-CRP and ejection fraction of individuals of NSTEMI, STEMI and Unstable angina.
Conclusions: The data concludes that hs-CRP is more closely related to LV function as assessed by ejection fraction. As our data demonstrated a significant correlation between high hs-CRP and reduced EF, increased hs- CRP may be a marker of LV dysfunction.
Keywords: hs-CRP, Acute coronary syndrome, Unstable angina, STEMI, NSTEMI.
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