Title: A Rare Case of Spinal Osteosarcoma with Extraosseous Component: Review of Literature for Role and Outcome of Radiation Therapy
Authors: Sameer Kr Verma, Ajeet K Gandhi, Madhup Rastogi, Satyajeet Rath, Sambit S Nanda, Siddharth Kumar, Ayushi Patni
DOI: https://dx.doi.org/10.18535/jmscr/v8i2.33
Abstract
Osteosarcoma (OS) most commonly occurs in metaphysis of long bones in young people. Spinal OS is a relatively uncommon tumor and difficult to treat owing to its close proximity to spinal cord. A 36 years old male with complaint of lower back pain for 3 months was diagnosed as a case of spinal OS of D12 vertebra with an extraosseous soft tissue component on radiological imaging and histopathological examination. The patient underwent D12, partial D11 and L1 laminectomy with tumour removal. Post operative imaging showed gross residual disease. External beam radiotherapy (EBRT) of 2000 cGy in 5 fractions to D10-L1 was delivered initially. As patient responded well to EBRT, additional 2000 cGy in 10 fractions was given followed by chemotherapy with good clinical and radiological response and symptomatic relief. With multimodality approach and careful selection of these patients, good local control and palliation can be achieved with early institution of radiotherapy in these patients.
Keywords: Osteosarcoma, Spinal osteosarcoma, Extraosseous spinal osteosarcoma, Radiotherapy in spinal osteosarcoma
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