Title: Multifarious Pediatric Seizures: It’s Correlation with EEG & Neuroimaging

Authors: Dr Sunil Kumar Agarwalla, Dr Kali Prasad Mishra, Dr Nawed Momin

 DOI: https://dx.doi.org/10.18535/jmscr/v8i2.18

Abstract

Seizures in pediatric age group are generally signaling a potentially serious underlying systemic or central nervous system disorders that require thorough clinical examination, investigation and management. It is therefore important to establish accurate diagnosis of seizures and its etiology to appropriately manage such patients. We carried out this study to evaluate different etiology of seizures and its correlation with abnormal EEG & abnormal neuroimaging in the age group of 1month to 14 years. 144 children presented with seizure to our department from September 2017 to August 2019 were enrolled in this prospective hospital based study. Detailed history, clinical examination, investigation with special emphasis to EEG & neuroimaging was done and different correlation was drawn by using SSPS 18.0 statistical analysis. Among 144 cases, 6 to 10 yr age group constituted maximum (45.14%) number of cases. Male to female ratio is 1.44:1. GTCS is the predominant pattern of seizure (63.89%) in all age groups. EEG abnormality is found in 47.92%, mostly in partial seizure type. Neuroimaging abnormality found in 27.08%. Maximum cases (25%) had infectious etiology. Pediatric seizure needs detailed history taking and careful examination. EEG has a role in specific seizure type; neuroimaging at times helps in diagnosis.

Keywords: Epilepsy, GTCS, EEG, Neuroimaging.

References

  1. Mikati MA, Hani AJ. Seizures in childhood. Kleigman RM, Stanton BF, Schor NF, St. Geme JW, Behrman RE. Nelson Textbook of Pediatrics. Philadelphia, Saunders. 2011;19:2013-7.
  2. Osuntokun BO. Epilepsy in African Continent. In: PenyJk(ed). Epilepsy: the eighth international symposium pp. New York, Ravan press.1977;365-78.
  3. Hauser WA, Kurland LT. The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967 . Epilepsia. 1975 Mar 1;16(1): 1-66.
  4. Washimkar SN, Holay MP, Fusey SM. Evaluation of focal seizure by computerized tomography. JAPI1996. 1996;44:959-60.
  5. Jin SH, Oslon DM. Etiology of neonatal seizures. NeoReviews 2004;5;e327-35.
  6. Yamamoto N, Watonobe K, Negoro T. Complex partial seizure in children. Neurology 1987;1982;23:61-9.
  7. Maytal J, Krauss Jm, Novak G, Nagelberg J, Patel M. The role of brain computed tomography in evaluating children with new onset of seizures in the emergency department. Epilepsia. 2000 Aug 1;41(8): 950-4.
  8. Thilothammal N. Approach to single enhancing CT lesions. Indian Journal of Practical Pediatrics. 2009;11(4):342-9.

Corresponding Author

Dr Kali Prasad Mishra

Junior Resident, Department of Pediatrics, MKCG MCH Berhampur