Title: A Rare Case of Idiopathic Intracranial Hypertension with Anemia: A Case Report

Authors: Aaminah Najmus Sahar, Khadija Akhtar Omer, Neha Naaz, Sufia Iram Irshad

 DOI: https://dx.doi.org/10.18535/jmscr/v8i2.17

Abstract

Idiopathic Intracranial hypertension (IIH) is a condition characterized by elevated Intra cranial pressure (ICP) due to no definite cause. It is a rare disorder and mostly occurs in females of reproductive age and obese individuals. Obesity and anemia are associated with elevated ICP, and contribute to the disease. If not managed at right time prolonged ICP can lead to papilledema and other visual abnormalities. The diagnosis is made with MRI, CT scan, lumbar puncture. The treatment focuses on reducing the elevated ICP and preserving the optic nerve function. Treatment is done with pressure reducing agents like Acetazolamide and supportive treatment may be given to reduce headache. This disease is prone to recurrence, thus management of weight and lifestyle modifications are necessary to prevent the relapse of disease.

Keywords: Idiopathic Intracranial Hypertension (IIH), Intracranial pressure (ICP), Acetazolamide, Obesity, Papilledema.

References

1.  Idiopathic Intracranial Hypertension-Michael Wall MD-Elsevier-Volume 9, Issue 1, Feb 1991

2. Re-evaluating the Incidence of Idiopathic Intracranial Hypertension in an Era of Increasing Obesity-Kilgore KP1, Lee MS2, Leavitt JA3, Mokri B4, Hodge DO5,  Frank RD5, Chen JJ6.-Elsevier –May 2017.

3. The Rational Management of Idiopathic Intracranial Hypertension-James J. Corbett, MD; H. Stanley Thompson, MD-JAMA Neurology-October 1989.

4. Anemia and papilledema.-Biousse V1,  Rucker JC, Vignal C, Crassard I, Katz BJ, Newman NJ.- Am J Ophthalmol. 2003 Apr;135(4):437-46.

5. Idiopathic intracranial hypertension: consensus guidelines on management-Mollan SP1,2, Davies B3, Silver NC4, Shaw S5,  Mallucci CL6,7, Wakerley BR8,9,  Krishnan A4, Chavda SV10, Ramalingam S10,  Edwards J11,12, Hemmings K13,  Williamson M13, Burdon MA2, Hassan-Smith G1,12, Digre K14, Liu GT15, Jensen RH16, Sinclair AJ1,2,12,17.- J Neurol Neurosurg Psychiatry. 2018 Oct;89(10): 1088-1100. doi: 10.1136/jnnp-2017-317440. Epub 2018 Jun 14

6. Safety and Tolerability of Acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial-ten Hove MW1, Friedman DI, Patel AD, Irrcher I, Wall M,  McDermott MP; NORDIC Idiopathic Intracranial Hypertension Study Group.- J Neuroophthalmol. 2016 March.

Corresponding Author

Aaminah Najmus Sahar

Department of Pharmacy Practice, Deccan School of Pharmacy (DSOP), OU, Hyderabad-500001, Telangana, India