Title: Various Presentations and Sites of Tuberculosis in Post Renal Transplant patients

Authors: Thakur Karan S., Kenwar Deepesh, Sharma Ashish

 DOI: https://dx.doi.org/10.18535/jmscr/v8i2.15

Abstract

Patients with Chronic Renal failure, with end stage kidney disease are the candidates undergoing renal transplant. Organ transplantation is followed by use of immuno-suppressants to prevent graft rejections. This lowers host immunity, which exposes the patients to various opportunistic infections. In developing countries like India where the burden of TB is very high, recipients of solid organs are under high risk to acquire tuberculosis. In general population Lung is the main site of development of TB. Other sites of involvement are lymph nodes, peritoneum and pleura. Fever and cough are the main presenting symptoms. In Transplant patients TB may develop in pulmonary or extrapulmonary sites.

Thus knowledge of TB, its clinical presentations, and its sites of involvement in renal transplant patients becomes very important.

Keywords: Renal Transplant, TB-Tuberculosis, ATT- Anti tubercular Therapy.

References

  1. Drobniewski FA, Ferguson J. Tuberculosis in renal transplant unit. Nephrology Dialysis Transplant 1996; 11: 768– 70.
  2. Canet E, Dantal J, Blancho G, Hourmant M, Coupel S. Tuberculosis following kidney transplantation. Nephrology Dialysis Transplantion 2011; 26: 3773–78.
  3. Norman SW, Christopher JK ,Ronan P, Kidney Transplantation, 26th ed. Bailey and love 2008:1423-26.
  4. Higuita L, Nieto RJ, Gonzalez DS, Kohn O, Alzate A, Echeverri C et al. Tuberculosis in renal transplant patients. J Bras Nefrol 2014;36:512-18.
  5. Jasmer RM, Nahid P, Hopewell PC. Latent tuberculosis infection.New English Journal Med 2002; 347: 1860–66.

Corresponding Author

Thakur Karan S.