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Category: Volume 07 Issue 10 October 2019
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Title: Histomorphological Spectrum of Ovarian Tumours in a Tertiary Care Centre in North India

Authors: Poonam Sharma, Subhash Bharadwaj

 DOI: https://dx.doi.org/10.18535/jmscr/v7i10.143

Abstract

Background: Ovarian tumours are a heterogeneous group of neoplasms with variable clinical, morphological and histological features. Malignant epithelial tumours are the commonest ovarian cancers and have high mortality rate. This study was undertaken to analyse histomorphological spectrum of ovarian neoplasm in women of different age groups

Aim & Objectives: To evaluate the frequency, distribution and the histomorphological spectrum of various ovarian tumours.

Material and Methods: This retrospective study was carried out in the Department of Pathology over a period of three years. All the ovarian tumour specimens received and fixed in 10% formalin formed the study material. 4-5 micrometer thick sections were cut and stained with H&E stain for Histopathological Evaluation.

Results: Age range of patients in our study was 21-76 years. Abdominal pain and lump were the commonest presenting symptoms. Majority of the tumours (86.6%) were benign tumours. Malignancy was seen in 9.8 % cases while borderline tumours were seen in 3.6 % cases. Epithelial tumours were the commonest tumours (69.6%) followed by germ cell tumours (25.8%). Serous cystadenoma was the commonest benign tumour and serous cystadenocarcinoma was the commonest malignant ovarian tumour.

Conclusions: Ovary is a common site of tumours in the female genital tract and usually presents with a variety of clinicomorphological and histological features. The prognosis and varying therapeutic strategies for ovarian tumours necessitate an accurate pathological evaluation. Newer techniques like IHC have made the diagnosis easier and more precise. However in institutes with limited resources, histopathological study is the gold standard in diagnosis and prognostic evaluation of these tumours.   

Keywords: Histopathology; Ovarian; Malignancy; Cystadenoma.

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Corresponding Author

Poonam Sharma

House no 109, Sector-7, Channi Himmat, Jammu (J&K), India – 180015