Title: Bronchial Neuroendocrine Tumour in Young Female: A Case Report

Authors: Dr Vaishali Walke, Dr Amrapali Gaikwad, Dr Suyog Ratnaparkhi, Dr Balwant Kowe

 DOI: https://dx.doi.org/10.18535/jmscr/v7i10.23

Abstract

  

The bronchopulmonary carcinoids are slow growing neuroendocrine tumours arising from enterochromaffin (EC) cells of bronchial epithelium comprising of 1% to 2% of all lung tumours. Central bronchial carcinoids are more common than the peripheral type. They are characterized by strikingly heterogeneous pathological features and clinical behavior. Surgical resection is the preferred treatment for localized carcinoid. Trans bronchoscopic resection may be an alternative for entirely endobronchial lesions.We report a case of 27 year old female presented with chest pain. High Resolution Computed Tomography (HRCT) reveals mass lesion of infective aetiology. Contrast Enhanced Computed Tomography (CECT) showed a well defined neoplastic growth occluding the right main bronchus. The diagnosis of Neuroendocrine Tumour / Carcinoid offered on endoscopic biopsy was confirmed on immunohistochemistry.

Keywords: Bronchial carcinoid, atypical carcinoid, neuroendocrine tumors.

References

  1. Zuetenhorst J M, Taal B G. Metastatic carcinoid tumors: A clinical review. Oncologist 2005; 10:123-31.
  2. Emeryk J, Czekajska-Chehab E, Korobowicz E, Korbel M, Wegrzyn-Szkutnik I, Milanowski J. Bronchial carcinoid in a 39-year-old man treated for bronchial asthma: A case report. Cases J 2008;2:7414.
  3. Davila D G, Dunn W, Tazelaar H D, Pairolero P C. Bronchial carcinoid tumors. Mayo Clin Proc 1993;68:795-803.
  4. Hage R, de la Rivière AB, Seldenrijk CA, van den Bosch JM. Update inpulmonary carcinoid tumors: A review article. Ann Surg Oncol 2003;10:697-704.
  5. Kulke MH, Mayer RJ. Carcinoid tumor. N Engl J Med 1999;340:858-68.
  6. Bhatia K, Ellis S. Unusual lung tumors. An illustrated review of CT features suggestive of this diagnosis. Cancer Imaging. 2006;6:72–82.
  7. Sadana M J, Mones JM, Garcia-Molinear M, Frable W J. Localized disordersof the bronchi & lung. In: Silverberg SG, editor. Principles & Practice of Surgical Pathology & Cytopathology. 3rd ed. New York, NY: Churchill Livingstone Inc.; 1997. p. 1189-297.
  8. Bora MK, Vithiavathi S. Primary bronchial carcinoid: a rare differential diagnosis of pulmonary Koch in young adult patient. Lung India: Official Organ of Indian Chest Society.  2012;29(1):59–62.
  9. Brambilla E, Lantuejoul S. Neuroendocrine neoplasms. In: Zander D S, Farver C F, editors. Pulmonary Pathology. 1st ed. Philadelphia, PA: Churchill Livingstone, Elsevier; 2008. p. 563-77.
  10. Kulkarni G, Gawande S, Chaudhari D, Bhoyar A. Bronchial carcinoid: case report and review of literature. MVP Journal of Medical Sciences. 2016;3(1):71-78.

Corresponding Author

Dr Suyog Ratnaparkhi

Plot no. 82, New Indira Colony, Bhagwan Nagar, Near Sainath School, Nagpur- 440027, Maharashtra, India