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Category: Volume 07 Issue 06 June 2019
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Title: A Study on Pattern and Outcome of Aluminium Phosphide (Celphos) Poisoning in Rural Tertiary Care Hospital in Uttar Pradesh

Authors: Manoj Kumar, Vijayavarman V, Sanjeev Kumar Pandey, Saleem Ahmad,  Arindam Das, Kiran K

 DOI: https://dx.doi.org/10.18535/jmscr/v7i6.173

Abstract

Background: Poisoning is a significant global public health problem.According to the WHO, 99 per cent of the fatal poisoning cases occur in developing countries. Aluminium phosphide (ALP), a fumigant used to protect grain stores, Poisoning is frequent in North India. In India, the correlates of suicide were Family problems, Illness, Unemployment, Addiction and poverty. Knowledge of pattern of poisoning is important to devise Treatment and prevention strategies.

Methods: This Hospital based Observational Study was conducted in the Department of Medicine, UPUMS, Saifai. The study was conducted from Jan 2017 to July 2018. A total of 69 cases of Aluminium Phosphide Poisoning were included in the study. Data regarding socio demographic profile, clinical profile, lab parameters, electrocardiography (ECG) and arterial blood gasses (ABG) were collected. Patients were followed up till discharge or expiry. Outcome of the patient was assessed at the time of discharge/expiry.

Results: The mean age of the study population was 24±5.9 years. 50.7% were female. 60.9% were married. Route of ingestion was oral (100%).31.9% patients had hypotension at presentation. During follow up 62 Patients (89.9%) developed hypotension. All 62 patients developed severe metabolic acidosis. ECG findings were sinus tachycardia in 46.4 %, followed by ventricular tachycardia in 24.6%. Mortality was seen in 62 cases (89.9%).

Conclusion: Aluminium Phosphide is a lethal poison and there is no antidote for this poison. Aluminium Phosphide poisoning is associated with very high mortality. Multiple approaches are required to reduce mortality associated with intentional poisoning.

Keyword: Aluminium Phosphide, Celphos, Poisoning.

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Corresponding Author

Dr Vijayavarman V

PG Junior Resident, Department of Medicine, U.P. University of Medical Sciences, Saifai,

Etawah (Uttar Pradesh)