Title: A Study of Phosphorus Levels as a Prognostic Indicator in Diabetic Ketoacidosis

Authors: Vijaya Kumar Rajendran, Dhananjayan Kannan

 DOI: https://dx.doi.org/10.18535/jmscr/v7i6.27

Abstract

Background: Diabetic ketoacidosis is an emergency complication of Diabetes Mellitus[1]. Phosphate depletion is common in DKA. This study was undertaken to find out mainly the use of serum phosphorus in Diabetic ketoacidosis as a prognostic indicator to assess the mortality and morbidity and determine the outcome.

Materials and Methods: 50 consecutive diabetic patients presenting with clinical and biochemical features of DKA admitted to IMCU Thanjavur Medical college hospital from January to August 2014 were studied.

Results: The study shows phosphorus levels at the time of admission can be used as a prognostic indicator in Diabetic Ketoacidosis.

Conclusion: High blood sugar is associated with a low phosphate value. Low serum phosphate was associated with a poor mental status and prolonged hospital stay.

Keywords: Acidosis, chi-square test, hyperglycemia, ketoacidosis, phosphorus.

References

  1. Derek Le Roith, Yehielzick. Recent advances in our understanding of insulin action and insulin resistance.
  2. Tracy l. setji, MD; Ann J.Brown, MD and Mark N.Feinglos, MD, CM. Gestational diabetes mellitus. Clinical diabetes. 2005; 23: 17-24.
  3. Henning TP, Cunningham TP. Biosensors for personal diabetes management. In Ramsay g, ed. Commercial biosensors. Newyork: John Wiley and Sons, 1998:3-46.
  4. Williams, M.H. (1999) Nutrition for health, fitness and sport, 6th Boston: Mcgraw-Hill.
  5. The expert committee on the diagnosis and classification of diabetes mellitus: report of the expert committee on the on the diagnosis and classification of diabetes mellitus. diabetes care 1997;20:11 83-1197.
  6. David B Snacks, David E Goldstein, Noel K Maclaren, Jay M Macdonald, Maian Parrott. Guidelines and recommendation for laboratory analysis in the diagnosis and management of DM. clinical chemistry 2002;48:436-472.

Corresponding Author

Dhananjayan Kannan

Senior Assistant Professor, Department of General Medicine, Government Kilpauk Medical College and Hospital, Chennai 600010, India