Title: A rare case of Primary Leptomeningeal Precursor B cell Lymphoblastic Lymphoma in a Pediatric Patient – Case report and Literature review

Authors: Malathi Mukunda Pai, Ashwini Nargund, Akkamahadevi Patil, Padma Maneya, Madhumathi Davanam Sathyanarayan

 DOI: https://dx.doi.org/10.18535/jmscr/v7i6.08

Abstract

We present a 4 year obese child, with no mass lesion in brain/CNS, normal chest, abdomen & normal peripheral smear, Bone marrow aspirate. There was Subdural Collection and enhancement. CSF cytology showed lymphoma/leukemic infiltration, Immunophenotyping was Precursor B cell lymphoma involving meninges. FISH study showed abnormal signal pattern for BCR-ABL gene indicating trisomy 9.

Keywords: CSF cytology; obese child; Immunophenotyping, B cell lymphoma.

References

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Corresponding Author

Dr Ashwini Nargund

Associate Professor, Department of Pathology, Dr M H Marigowda road, Kidwai Cancer Institute, Bengaluru, India