Title: Bode Index in COPD Patients during Acute Exacerbations and its Influence on Treatment Outcome – An Observational Study
Authors: Dr Durga Balagopalan, Dr Ponneduthamkuzhy Thomas. James, Dr Anoop Muthiraparambathu
DOI: https://dx.doi.org/10.18535/jmscr/v7i4.186
Abstract
Background: Exacerbations of COPD can range from those that are nuisances to those that are life threatening, but treatment can shorten the duration of illness and improve outcomes.
So this study intended to find out the mortality rate in patients with COPD acute exacerbations and also to find out simple clinical and laboratory parameters that may predict the mortality in these patients and also influence of BODE Index on the treatment outcome of COPD exacerbations.
Objective: To find out the influence of BODE index in the treatment outcome of COPD during acute exacerbation.
Materials and Methods: This study was an observational study. All cases of COPD diagnosed by a physician and on treatment for more than one year, admitted in Institute of Chest Diseases with exacerbation were included in the study. BODE Index was calculated.
Data were collected and tabulated. Statistical analysis was done using SPSS Software version 12.0 and Epi Info version 3.4.1
Results: This study gives a brief idea about the mortality rate in COPD acute exacerbations.. All the patients were males. 34 patients died during treatment. In the study, most of the patients belong to the age group between 60 – 70 years. BODE score >7 was found to be a predictor of mortality in these patients by univariate analysis (p value =0.036).But there was no statistical significance with multivariate analysis for this observation.
Conclusion: Mortality rate of COPD acute exacerbations was 33.66% in this observational study. BODE score >7 was found to be a predictor of mortality in COPD acute exacerbations by univariate analysis.
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