Title: Pediatric Oral Manifestations of HIV- A Case Report with Review

Authors: Dr M. Chandrasekhar, Dr Marisetty Charitha, Dr Ayesha Thabusum, Dr G. Chandrasekhar, Dr Naresh Naik

 DOI: https://dx.doi.org/10.18535/jmscr/v7i4.170

Abstract

Oral Manifestations of immune suppression may take the form of opportunistic infection, and neoplasia. While this case has focused on gingival manifestations, these tissues cannot be evaluated in isolation. The presence of involvement of other oral tissues such as the cheek or tongue with manifestations associated with HIV such as hairy leukoplakia, Kaposi’s sarcoma at these sites, and candidiasis in addition to periodontal manifestations may further increase the clinical suspicion of underlying immunesuppression and progression of the immunosuppressive state.

Keywords: Child, Acquired Immunodeficiency Syndrome, Oral manifestations.

References

  1. Tonelli SQ, Oliveira WF, Oliveira GA, Popoff DAV, Coelho MQ, Barbosa Júnior ES. Manifestações bucais em pacientes pediátricos infectados pelo HIV: uma revisão sistemática da literatura. RFO 2013; 18(3):365-372
  2. Rosendo IA, Ferreira SMS, Pugliesi DM. Avaliação das condições bucais em crianças infectadas pelo HIV atendidas em um posto de assistência municipal de Maceió-AL. Estudo longitudinal. Revista Semente 2011; 6(6):53-61.
  3. Ogunbosi, BO, Oladokun RE, Brown BJ, Osinusi KI. Prevalence and clinical pattern of paediatric HIV infection at the University College Hospital, Ibadan, Nigeria: a prospective cross-sectional study. Ital J Pediatr 2011; 37:29.
  4. Glick M. Orofacial disorders in children with HIV disease. Dent Clin N Am 2005; 49(1):259-271.
  5. Leao JC, Ribeiro CM, Carvalho AA, Frezzini C, Porter S. Oral complications of HIV disease. Clinics (Sao Paulo) 2009; 64(5):459-470.
  6. Jose R, Chandra S, Puttabuddi JH, Vellappally S, Al Khuraif AA, Halawany HS, Abraham NB, Jacob V, Hashim M. Prevalence of oral and systemic manifestations in pediatric HIV cohorts with and without drug therapy. Curr HIV Res 2013; 11(6):498-505.
  7. Domaneschi C, Massarente DB, de Freitas RS, Sousa Marques HH, Paula CR, Migliari DA, Antunes JL. Oral colonization by Candida species in AIDS pediatric patients. Oral Dis 2011; 17(4):393-398.
  8. Konstantyner TC, Silva AM, Tanaka LF, Marques HH, Latorre MR. Factors associated with time free of oral candidiasis in children living with HIV/AIDS, São Paulo, Brazil. Cad Saude Publica 2013; 29(11):2197- 2207.
  9. Greenspan, J. S., Barr, C. E., Sciubba, J. J. & Winkler, J. R. (1992) Oral manifestations of HIV infection, Definition, diagnosticcriteria and principles of therapy. Oral Surgery Oral Medicine Oral Pathology 73,142–144.
  10. Glick, M., Muzyka, B. C., Salkin, L. M. & Lurie, D. (1994) Necrotizing ulcerative periodontitis: a marker for immune deterioration and a predictor for the diagnosis of AIDS. Journal of Periodontology 65, 393–397.
  11. MacPhail LA, Greenspan D, Feigal DW, Lennette 1. ET, Greenspan JS. Recurrent aphthous ulcers in association with HIV infection. Oral Surg Oral Med Oral Pathol 1991; 71: 678-83.
  12. Miziara ID, Filho BCA, Weber R. AIDS and recurrent aphtous stomatitis. Braz J Otorhinolaryngol 2005; 71: 517-20.
  13. Classification and diagnostic criteria for oral lesions in HIV infection. J Oral Pathol Med 1993; 22: 289-91.
  14. Phelan JA, Eisig S, Freedman PD, Newsome N, Klein RS. Major aphthous-like ulcers in patients with AIDS. Oral Surg Oral Med Oral Pathol 1991; 71: 68-72.

Corresponding Author

Dr M. Chandrasekhar

Department of Oral Medicine and Radiology, Government Dental College and Hospital, Kadapa

Andhra Pradesh, India