Title: Screening for Deep Vein thrombosis and pulmonary embolism in bed ridden patients in a tertiary care hospital in Central India

Authors: Kapil Kant Tripathi, TN Dubey, KK Kavre, BS Yadav

 DOI: https://dx.doi.org/10.18535/jmscr/v7i4.163

Abstract

Introduction: Venous thromboembolism (VTE) is a common and potentially life threatening condition. Among cardiovascular diseases VTE is third most common cause of death. Many studies done in western countries have shown this condition to be very common. Studies done in Asian countries showed that this condition is not uncommon in asian patients as was thought earlier. Hence this study was planned to evaluate incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) in bed ridden patients.

Materials and Methods: This was an observational study in which 200 patients who were bedridden for more than 3 days were enrolled. All the routine examination like coagulation profile, D-Dimer, venous colour Doppler, and CT angiography was done. Data analysis was done using SPSS software. Data was expressed as mean ± SD. P value <0.05 was considered significant.

Result: Mean age of patients in the study was 43±14 out of which 117 were female and 83 were male subjects. Mean D-dimer value of patients in the study was 714±80. Out of 200 patients enrolled in the study 42 patients had DVT and 14 patients had PE.

Conclusion: As observed in the study there is high a risk of developing DVT and PE in the patient even if the patient is non- ambulatory for 3 days. Thus bed ridden patients should be screened for DVT, also anticoagulation should be started in such patients prophylactically.

Keywords: Deep Vein Thrombosis (DVT), Bed ridden patients, Venous thromboembolism (VTE).

References

  1. Agarwal S,  Lee AD,Raju RS, Stephen Venous thromboembolism: A problem in the Indian/Asian population? Indian J Urol. 2009 Jan-Mar; 25(1): 11–16.
  2. Hirsh J, Hoak J. Management of deep vein thrombosis and pulmonary embolism: A statement for healthcare professionals. Council on Thrombosis (in consultation with the Council on Cardiovascular Radiology), American Heart Association. 1996;93:2212–45.
  3. Angral R, Islam MS2, Kundan S. Incidence of deep vein thrombosis and justification of chemoprophylaxis in Indian patients: A prospective study. Bangladesh Med Res Counc Bull 2012; 38: 67-71
  4. Dhillon KS, Askander A, Doraisamy S. Postoperative deep vein thrombosis in Asian patients is not a rarity: A prospective study of 88 patients with no prophylaxis. J Bone Joint Surg Br 1996; 71: 427-30.
  5. Nathan S, Aleem MA, Thiagaranjan P, Das D.S. The incidence of proximal deep vein thrombosis following total knee arthroplasty in an Asian population: a Doppler ultrasound study. J orthop. Surg (Hong Kong) 2003; 11: 184-9
  6. Lee AD, E. Stephen, S. Agarwal, P. Premkumar. Venous Thrombo-embolism in India. Eur J VascEndovascSurg (2009) 37, 482e485
  7. Naqvi SE, Haseen MA, Beg MH, Ali E, Khan T. Deep vein thrombosis: An experience of 25 years from north India. Indian J Vasc Endovasc Surg 2016;3:2-6.
  8. Borde TD, Prasad C, Arimappamagan A, Srinivas D, Somanna S. Incidence of deep venous thrombosis in patients undergoing elective neurosurgery – A prospective cohort based study. Neurol India 2017;65:787-93.
  9. Dhillon KS, Askander A, Doraisamy S. Postoperative deep vein thrombosis in Asian patients is not a rarity: A prospective study of 88 patients with no prophylaxis. J Bone Joint Surg Br 1996; 71: 427-30.
  10. Agarwala S, Bhagwat AS, Modhe J. Deep vein thrombosis in Indian patients undergoing major lower limb surgery. Indian J Surg 2003;65:159e62.
  11. Dhillon KS, Askander A, Doraismay S. Post-operative deep veinthrombosis in Asian patients is not a rarity. J Bone Joint Surg Br 1996 May;78(3):427e30.
  12. Ko PS, Chan WF, Siu TH, Khoo J, Wu WC, Lam JJ. Deep venous thrombosis after total hip or knee arthroplasty in a”low-risk” Chinese population. J Arthroplasty 2003;18:174-9.
  13. Kamerkar DR, M. Joseph John, Sanjay C. Desai, Liesel C. Dsilva, and Sadhna J. Joglekar. Arrive: A retrospective registry of Indian patients with venous thromboembolism. Indian J Crit Care Med. 2016 Mar; 20(3): 150–158.
  14. Angral R1, Islam MS2, Kundan S. Incidence of deep vein thrombosis and justification of chemoprophylaxis in Indian patients: A prospective study. Bangladesh Med Res Counc Bull 2012; 38: 67-71
  15. Mavalankar AP, et al. Routine chemoprophylaxis for DVT in Indian patients: Is it really justified? Indian Journal of Orthopaedics 2007; 41: 188-93.
  16. Wells PS, Anderson DR, Bormanis J, et al. Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet 1997; 350: 1795–98.
  17. Wells PS, Anderson DR, Rodger M, et al. Excluding pulmonaryembolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model andd-dimer. Ann Intern Med 2001; 135: 98–107.

Corresponding Author

TN Dubey

Professor and Head, Department of Medicine, Gandhi Medical College, Bhopal, MP, India