Title: A Prospective Study of Clinical Profile of Patients Diagnosed with Malaria
Authors: Dr Dharmendra Singh, Dr Sanjay Dhawale, Dr Amit Garg
DOI: https://dx.doi.org/10.18535/jmscr/v7i4.123
Abstract
Background: Malaria is a major public health problem in India. Previous reports suggest that India reported 1.6 million cases and 1100 malaria deaths in the year 2015.
Aims and Objectives: To study the clinical profile of patients of malarial coming to a tertiary care hospital.
Materials and Methods: Hundred malaria patients were studied in the Department of Medicine, J.A. Group of Hospitals, GRMC Gwalior. Data on presenting complaints and general examination was performed. Complete haemogram, liver function test (serum bilirubin, SGOT, SGPT, ALP), bleeding time, clotting time was estimated.
Results: Maximum patients were in the age group of ≤30 years (56%) with equal distribution of gender. Majority had (19%) tachycardia, 9% had hypotension, 5% had tachypnea and 6% had hypoglycemia. Leucocytopenia was reported in 25% and leucocytosis in 2% patients. Majority (20%) had serum bilirubin of>2mg/dl, SGPT was increased in 35%, blood urea was increased in 7% and creatinine was increased in 6% malaria patients. Distribution of hepatomegaly and spleenomegaly was equally distributed among normal and abnormal SGPT and hemoglobin values.
Conclusion: Malaria was most common in working age group; fever, headache, nausea and vomiting were the most common symptoms. Pallor and icterus was the most common signs. An early diagnosis and treatment goes a long way in preventing avoidable deaths due to malaria.
Keywords: Leucocytopenia, protozoal disease, mortality, liver function test, organomegaly.
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