Title: Comparison of Post Operative Recovery Characteristics with Isoflurane and Sevoflurane in Patients Undergoing Laparoscopic Cholecystectomy: A Randomised Control Study
Authors: Raja Avinash, Praveen Kumar Singh, Priyesh Kumar, Ravi Kant
DOI: https://dx.doi.org/10.18535/jmscr/v7i4.106
Abstract
Background: Inhaled volatile anesthetic remains the most widely used drug for the maintenance of general anesthesia. These volatile anesthetic namely isoflurane, sevoflurane are in current practice for maintenance of anesthesia. Management of haemodynamic stability is the most important part of standardized balanced technique.
Material & Methods: The study was conducted in IGIMS, Patna and SKMCH, Muzaffarpur. The study was prospective and randomized, conducted in indoor patients belonging to either sex, after obtaining informed consent from each patient. Most of the patients are from urban population. Sixty ASA physical status I-II patients of either sex, aged 35-70 years and weighing 40-70 kg, scheduled for elective laparoscopic cholecystectomy under general anesthesia were randomly divided into three groups – group A and B with equal numbers
Results: We compared the recovery time after closing the inhalational agent isoflurane or sevoflurane. It was assess by eye opening, hand grip, extubation and answering name. It is less for Sevoflurane than Isoflurane.
Conclusion: In elective laparoscopic cholecystectomy operations agent of choice for maintenance of anesthesia will be sevoflurane followed by isoflurane according to early recovery characteristics.
References
1.Comparison of Recovery Profile After Ambulatory Anesthesia with Propofol, Isoflurane, Sevoflurane and Desflurane: A Systematic Review. Gupta, Anil, MD, FRCA, PhD*†; Stierer, Tracey, MD*; Zuckerman, Rhonda, MD*; Sakima, Neal, MD*; Parker, Stephen D., MD*; Fleisher, Lee A., MD*
- Anesthesia for laparoscopic cholecystectomy: comparative evaluation--desflurane/ sevoflurane vs. propofol. Erk G1, Erdogan G, Sahin F, Taspinar V, Dikmen B.
- Target Controlled Infusion versus Sevoflurane/Desflurane Anesthesia for Laparoscopic Cholecystectomy: Comparison Postoperative Nausea/Vomiting and Extubation Time. Prathep S, Mahattanaporn S, Wasinwong W. J Med Assoc Thai. 2015 Dec;98(12):1187-92.PMID: 27004303
- The impact of isoflurane, desflurane, or sevoflurane on the frequency and severity of postoperative nausea and vomiting after lumbar disc surgery. Wallenborn J1, Rudolph C, Gelbrich G, Goerlich TM, Helm J, Olthoff D.
- Sevoflurane: an ideal agent for adult day-case anesthesia? Ghatge S, Lee J, Smith I.Acta Anaesthesiol Scand. 2003 Sep; 47(8):917-31.
- Randomized, controlled trial comparing the effects of anesthesia with propofol, isoflurane, desflurane and sevoflurane on pain after laparoscopic cholecystectomy. Ortiz J1, Chang LC2, Tolpin DA2, Minard CG3, Scott BG4, Rivers JM2.
- Comparison of recovery profile for propofol and sevoflurane anesthesia in cases of open cholecystectomy. Shiv Kumar Singh, Amit Kumar, Reena Mahajan, Surabhi Katyal,1 and Sfurti Mann