Details
Category: Volume 07 Issue 03 March 2019
Hits: 1377

Title: Acute Reversible Hand Ischemia after Clindamycin injection

Authors: Harharpreet Kaur, Santosh Minhas, S.S. Minhas, Kiran Kumar Singal, Sukhraj Pal Singh

 DOI: https://dx.doi.org/10.18535/jmscr/v7i3.234

Abstract

Intravenous (IV) therapy is associated with a number of potential complications including ecchymosis, extravasation, hematoma, phlebitis, skin necrosis and air embolism. We report a case in which an intravenous injection of clindamycin dramatically produced deep cyanosis, ischemia and swelling of the injected hand which improved within 2-3 days. The underlying mechanism was possibly a vasospasm induced by the irritant action of the drug.

Keywords: Clindamycin; Injection; Cyanosis; Swelling; Hand;Vasospasm.

References

  1. Lateef F: Extravasation: there could be more than meets the eye! J Trauma Crit Care. 2017;1:1
  2. Goutos, Cogswell LK, Giele H. Extravasation injuries: a review. J Hand. SurgEur Vol. 2014 Oct;39(8):808-18.
  3. Dahal P, Shrestha JM: Extravasation Injury of the Upper Limb by Intravenous Clindamycin Postgraduate Medical Journal of NAMS 2011Volume 11,Number 2
  4. Alexander, R. S.: The peripheral venous system. in Hamilton. W. F. and Dow. P.: Hand- book of physiology, Section 2, Circulation, 31, Washington, D. C., 1963, vol. 2, p. 1086, American Physiological Society
  5. Walker T. Gregory (. "Acute Limb ischemia". Techniques in Vascular and Interventional Radiology. (2009)12 (2): 117–129.
  6. Ellertson DG, Lazarus HM, Auerbach R. Patterns of acute vascular injury after intra-arterial barbiturate injection. Am J Surg. 1973;126:813-817
  7. Webster J L. Oedema and cyanosis of the Hand following injections into the vein on the Dorsum of the hand A Case Report Brit. J. Anaesth. (1964), 36, 50
  8. Cohen S. Accidental intra-arterial injections of drugs. Lancet 1948; 2: 361–71
  9. Kaplan EB, Spinner M. Kaplan’s Functional and Surgical Anatomy ofthe Hand. 3rd ed. Philadelphia, Pa: Lippincott; 1984.
  10. Baillie, T. W. Accidental intra-arterial injection of thiopentone on the back of the hand. (1958). Brit. J.Anaesth., 30, 373.

Corresponding Author

Dr Harharpreet Kaur

Professor Medicine, MM Medical College, Kumarhatti, Distt. Solan, Himachal Pradesh, India

Ph 9872777800, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.