Title: A Study of Coronary Risk and LDL in Type II Diabetic Patients

Authors: M.Ramanathan, M.F. Mohamed Azath Ali, S.M.Rajeswari

 DOI: https://dx.doi.org/10.18535/jmscr/v7i3.219

Abstract

A prospective study was carried out to find the percentage of dyslipidemia in type II diabetics in comparison with non diabetic individuals, to study the pattern of dyslipidemia, categorize the levels of LDL, HDL and triglycerides into higher, borderline and lower risk of developing coronary heart disease in type II diabetics and categorize the type of and level of dyslipidemia in symptomatic and asymptomatic coronary artery disease.

References

  1. Richard WN, Stuart WZ, Richard WJ, Mansoor K. Heart disease in diabetes. In Ronald CK. Gordon CW (Eds), Joslin Diabetes mellitus 13th ed. Philadelphia, Lea and Febiger 1994; 836-57.
  2. Kannel WB, McGee DL. -Diabetes and glucose tolerance as risk ' factors for cardiovascular disease : The Framingham Study. Diabetes Care 1979; 2: 120-126.
  3. Wingard DL, Barrett-Connor E. Heart disease and diabetes. In : National Diabetes Data Group. Diabetes in America. 2nd ed. Washington, D.C.: Government Printing Office, 1995 : 429-48.
  4. Pyorala K, Laakso M, Uusitupa M. Diabetes and atherosclerosis: An Epidemiologic view. Diabetes Metab Rev 1987; 3:463-524.
  5. Stamler J, Vaccaro 0, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993 ; 16 : 434-444.
  6. Pekkanen .1, Linn S, Heiss G. Ten-year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease. N Engl J Med 1990 ; 322: 1700-1707.
  7. Rosengren A, Hagman M, Wedel 14, Wilhelmsen L. Serum cholesterol and long-term prognosis in middle-aged men with myocardial infarction and angina pectoris: a 16-year follow-up of the Primary Prevention Study in Goteborg, Sweden. Eur Heart J 1997 ; 18 : 754-761.
  8. Rosengren A, We-lin L, Tsipogianni A, Wilholmsen L. Impact of cardiovascular risk factors on coronary heart disease and mortality among middle aged diabetic men: a general population study. BM,' 1989 ; 299: 1127-1131
  9. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). JAMA 1993 ; 209 : 3015-3023.
  10. American Diabetes Association. Management of dyslipidemia in adults with diabetes. Diabetes Care 1998 ; 21 : 179-182
  11. Miettinen H, Lehto S, Salomaa VV. Impact of diabetes on mortality after the first myocardial infarction. Diabetes Care 1998 ; 21 : 69-75
  12. M. Haffner, SeppoLehto -,Tapani Ronnemaa. Mortality from Coronary heart disease in Subjects with Type 2 Diabetes and in Non Diabetic Subjects with and without Prior Myocardial Infarction. NEJM 1998 ; 339: 229- 234
  13. Pyorala K, Pedersen TR, Kjekshus J, Faergeman 0, Olsson AG, Thorgeirsson G. Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease: a subgroup analysis of the Scandinavian Simvastatin Survival Study (4S). Diabetes Care 1997 ; 20 : 614-620.
  14. Sacks FM, Pfeffer MA, Moye LA. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl Med 1996 ; 335: 1001-1009
  15. Abbott RD, Donahue RP, Kannel WB, Wilson PW. The impact of diabetes on survival following myocardial infarction in men vs. women: the Framingham Study. JAMA 1988 ; 260 : 3456-3460.

Corresponding Author

Dr M. Ramanathan

Assistant Professor, Dept. of General Medicine, Govt KAPV Medical College, Tiruchirapalli, India