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Category: Volume 07 Issue 03 March 2019
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Title: Albuminuric Status in Patients with Clinical Diabetic Retinopathy in Type II Diabetes Mellitus

Authors: Dr Sruthi G, Dr Shankar C, Dr Stephen Sudhakar K

 DOI: https://dx.doi.org/10.18535/jmscr/v7i3.174

Abstract

Introduction: Aim of this study was to correlate diabetic retinopathy and its severity with type of albuminuria and renal status of the patients

Methods: In this observational correlative study 100 patients suffering from diabetes type II were examined. Fundus examination was performed. Ratio of urinary albumin to creatinine, serum potassium and HbA1C were measured. Fundus fluorescein angiogram was done in patients with clinical maculopathy and in patients with suspected PDR to confirm the diagnosis

Results: Among the study population, 53 participants were male and 47 were female. Majority of patients with clinical diabetic retinopathy of varying grades had microalbuminuria (57%) followed by normoalbuminura (25%) and macroalbuminuria (18%). The difference in the proportion of grade of diabetic retinopathy across albuminuria was statistically significant (p value <0.001). Among studied population PDR & advanced diabetic eye disease was found in 8% of normoalbuminura patients, 10.5% of microalbuminuria patients and 55.6% of macroalbuminuria patients.  Urine microalbumin to creatinine ratio increased with severity of grade of retinopathy which was found to be statistically significant (P Value <0.001)

Conclusion: Macroalbuminuria was associated with severe grade of diabetic retinopathy in type II diabetic patients. Urine microalbumin to creatinine ratio was associated with increased severity of grade of retinopathy. Maculopathy was not associated with albuminuria in our study.

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Corresponding Author

Dr Stephen Sudhakar K