Title: Rare Case of Metastatic Gall Bladder Neuroendocrine Carcinoma: A Case Report
Authors: Harsha Balachandran, Sajeed A, Sindhu Nair, Suriyan S Nair
DOI: https://dx.doi.org/10.18535/jmscr/v7i3.154
Abstract
Neuroendocrine tumours (NET) of the gallbladder (GB) are nonspecific in nature. The diagnosis is usually made after cholecystectomy for cholelithiasis. The main treatment option is surgery. The role of adjuvant therapy after complete resection is undefined, whereas in metastatic disease, chemotherapeutic drugs have shown some activity. Here, we report the case of a 65 year old female who was presented to the hospital with swelling in the left neck and back pain radiating to chest. Fine Needle Aspiration (FNA) of left supraclavicular lymph node done showed poorly differentiated carcinoma with neuroendocrine features. Subsequent Contrast Enhanced Computed Tomography (CECT) imaging was suggestive of GB malignancy along with extensive lymph node metastasis. Positron emission tomography (PET) scan confirmed the gall bladder malignancy with extensive lymph node metastasis. Six cycles of chemotherapy with Cisplatin and Etoposide was given with the diagnosis of metastatic GB-NET, for which she received partial response.
Keywords: Neuroendocrine tumour (NET), Gall bladder (GB), Positron Emission Therapy(PET)
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