Title: A Study on Clinical and Laboratory Findings in Early Neonatal Sepsis in Tertiary Care Hospital
Authors: Dr Lavanya Bai Munavath, Dr Sravan Kumar Kusuma, Dr Attada Ajay Kumar
DOI: https://dx.doi.org/10.18535/jmscr/v7i2.182
Abstract
Introduction: Neonatal sepsis is a clinical syndrome of bacteremia with systemic signs and symptoms of infection within the first 28 days of life .It is caused by the microorganisms or their toxic products in the circulation. It is further classified as early onset (within 72 hrs of life) EOS and late onset (LOS). EOS is more common than LOS in which the EOS causes a mortality rate of 15-40% of total 30-50% of neonatal sepsis.
Materials & Methods: A descriptive study of 200 neonates were included in the study, conducted in King George Hospital, department of pediatrics, Visakhapatnam from January 2018 to July 2018.100 term and 100 preterm neonates with clinically suspected were selected by using New Ballard score as gestational age assessment, all neonates are evaluated with detailed history of mother and perinatal events and bacteriological profile in these 200 neonates studied by various types of culture and compared with serum samples.
Results: Premature rupture of membranes and meconium stained amniotic fluid are common antenatal complications, Respiratory distress is the most common clinical presentation seen in 52% of cases with preterm significance. CRP is the rapid diagnostic test has high sensitivity in both preterm and term neonates.
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