Title: Correlation of inflammatory marker High-sensitive C-reactive protein (Hs-CRP) with risk factors of nephropathy in type 2 diabetes

Author: Surendra Prasad Singh

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.135

Abstract

Aim: The goal of this observational trial is to evaluate the Correlation of inflammatory marker High-sensitive C-reactive protein with risk factors of nephropathy in type 2 diabetes.

Methods: 82 type 2 diabetes patients (T2DM) was selected to conduct the observational study. A standard questionnaire was used to collect the data regarding major environmental risk factor for diabetic nephropathy of T2DM like age, duration of diabetes, smoking, anti-diabetic medication and anti-hypertensive medication. Blood sample was collected to perform pathological test like Fasting Plasma Glucose (FPG), Post Prandial Plasma glucose (PPG) and high sensitive C reactive protein (Hs-CRP).

Result: Result of this observational study reveals that the risk factors for diabetic nephropathy of T2DM like age (p=0.231), duration of diabetes (p=0.342), smoking (p=0.931), anti-diabetic medication (p=0.537) and anti-hypertensive medication (p=0.425) wasnot found to be correlated with Hs-CRP levels.

Conclusion: This study concludes that inflammatory marker High-sensitive C-reactive protein insignificantly correlated with the major environmental risk factor for diabetic nephropathy of T2DMlike age, duration of diabetes, smoking, anti-diabetic medication and anti-hypertensive medication.

Keywords: Hs-CRP, Diabetic nephropathy, T2DM, Risk factors.

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Corresponding Author

Surendra Prasad Singh

Department of Community Medicine, Patna Medical College & Hospital, Patna, Bihar, India