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Category: Volume 07 Issue 02 February 2019
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Title: Analysis of Molar Pregnancy in a Tertiary Care Centre of Muzaffarpur, Bihar: A two years Retrospective Study

Authors: Amrita Pritam­­­­­­­­, Pallawi Singh, Abha Sinha

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.126

Abstract

Objective: A Hydatidiform mole is characterized by a hydropic swelling of the chorionic villi and trophoblastic proliferation. It is classified as a complete hydatidiform mole and partial hydatidiform mole on the basis of histopathological features and karyotype. Women of both extreme of reproductive age are most vulnerable. Untreated molar pregnancies almost always cause uterine bleeding that varies spotting to profuse hemorrhage. This study was conducted to calculate incidence of molar pregnancy, associated demographic factors and to analyze the various aspects of molar pregnancy at our hospital.

Materials and Methods: A retrospective study was carried out for over a period of two years from April 2015 to March 2017 in the Department of Obstetrics and Gynecology at S. K. Medical College, Muzaffarpur, Bihar to calculate the incidence of molar pregnancy, to study the associated demographic factors and to analyze the various aspects of molar pregnancy at our hospital. All the relevant data were collected from hospital records and departmental registers. Collected data were computed and analyzed statistically.

Results: A total of 37 cases of molar pregnancies were recorded for the period of two years. During this study period, the total number of deliveries was 18,143. Hence the incidence of molar pregnancy in our study is 0.815 in 400 deliveries. 64.86% cases were of age group 20-30 years. Uterine size larger as compared to gestation age was observed in 78.37% cases. Serum β hCG level were between 50000-100000 in 59.46% of cases. 75.67% cases were presented with a gestational age of 10-20 weeks.

Conclusion: Early detection of high risk pregnancies and their prompt management and referral is necessary. Early detection by ultrasonography and serum β hCG value is necessary for proper management of molar pregnancies. Prophylactic chemotherapy is also of significance in management and to prevent further recurrence of molar pregnancy.

Keywords: Complete mole, Hemorrhage, Hydatidiform mole, Invasive mole, Partial mole.

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Corresponding Author

Amrita Pritam­­­­­­­­

Senior Resident, Department of Obs & Gynae, Sri Krishna Medical College & Hospital, Muzaffarpur, Bihar