Title: Comparison of Anneroth’s and Broder’s grading systems in oral squamous cell carcinoma- A 5 year study
Authors: Prof. Dr Shikha Ghanghoria, Dr Sunil Jaiswal, Dr Priyanka Kiyawat, Prof. Dr Arvind Ghanghoria
DOI: https://dx.doi.org/10.18535/jmscr/v7i2.124
Abstract
Background: Oral cavity is one of the leading site of cancer. The incidence of oral cancer in India is 30-50% of whole body tumors .Histological grading is an important diagnostic tool to predict the clinical and biological behaviour of oral squamous cell carcinoma. Analysis of the prognostic factors is important for predicting prognosis and reducing mortality in these patients. 1927 Broder’s grading system was formed for grading of oral squamous cell carcinoma, this system was applied for many years, then in 1978 Anneroth’s multifactorial grading system was established by Dr Anneroth, for evaluation of prognosis and prediction of survival period for oral squamous cell carcinoma patients.
Objective: To Compare Anneroth and Broder’s grading systems in oral squamous cell carcinoma and to evaluate the Anneroth’s grading as a standard as compare to Broder grading system.
Material and Method: Retrospective study was done on total 600 Biopsy and radical specimen cases which were reported as SCC in last 5yrs,were collected from record room of histopathology section in MGM Medical college & M.Y. Hospital Indore(M.P.) are included in study . All cases were reclassified according to Anneroth’s system. Broder’s system is based on only differentiation of cells while six parameters of Anneroth’s system gives a detail about degree of keratinisation, nuclear pleomorphism, number of mitosis/hpf, pattern of invasion, stage of invasion and lympho plasmacytic infiltration.
Result: In this study ,according to Border’s grading system out of 600 cases 52% cases were grade I,40% cases were grade II and 8% cases were grade III while according to Anneroth’s grading system 37% were grade I,55% were gradeII,7.0% were grade III and 1.0% were grade IV. Anneroth’s grading system is more informative and gives better result regarding prognosis, action taking time and prediction of survival period than Broder’s System.
Conclusion: Anneroth’s system of grading can be taken as standard system for evaluation of prognosis and prediction of survival period in patient of OSCC.
Keywords: Oral Squamous Cell Carcinoma, Malignancy Grading System, Metastasis.
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