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Category: Volume 07 Issue 02 February 2019
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Title: Redefining risk factors associated with Acute Myocardial Infarction (AMI) and to define independent predictors of mortality and morbidity in AMI

Authors: Viral Sangwan, Dr Roopa Malik, Dr Manjari Garg, Dr Sanjay Fotedar

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.84

Abstract

Objective: To study various risk factors associated with Acute Myocardial Infarction , to define independent predictors of mortality and morbidity in AMI and to compare our mortality rate with those published from centre having PCI/CABG facilities.

Method: This was a prospective study on 200 consecutive patients of acute myocardial infarction admitted to intensive cardiac care unit of PGIMS Rohtak for one year duration. Clinical and demographic profile, risk factors, morbidity and mortality of AMI patients were studied, analyzed and compared to results from centers having PCI/CABG facilities.

Results: Factors associated with increased morbidity are age>70 years, female gender, >10 hours duration of chest pain, tachycardia (>100bpm), hypotension (systolic BP 100mmHg), hypertension, socioeconomic status (class III, IV, V), diabetes, obesity, sedentary life style, LDL cholesterol<140mg%, S. homocystine >12umol/L, S. cholesterol>240mg/dl, presence of multiple risk factors. Independent predictors of mortality include age>70 years, female gender, duration of chest pain >10 hours, tachycardia, hypotension, not receiving treatment outside hospital, previous history of MI, history of diabetes, physical inactivity, S. total cholesterol >240mg%, LDL cholesterol >130mg%, HDL cholesterol <40mg%, S. homocystine >12umol/L and presence of multiple risk factors. On follow up, most common complication was LVF and post MI angina. Total mortality rate in this one year study was 3%.Total mortality rate of last 5 years data was 4.49%.Centers having PCI facilities had 6.4% mortality in AMI patients.

Keywords: Acute myocardial infarction, risk factors, mortality, morbidity.

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Corresponding Author

Viral Sangwan
PGIMS Rohtak
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