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Category: Volume 07 Issue 01 January 2019
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Title: A rare case of Langerhans Cell Sarcoma in a child mimicking a Lymphoma

Authors: Akkamahadevi Patil, Champaka G*, Usha A, Premalata C.S, Malathi Mukunda Pai, Rekha V. Kumar, Padma Maneya

 DOI: https://dx.doi.org/10.18535/jmscr/v7i1.201

Abstract

Langerhans cell sarcoma (LCS) is a high grade neoplasm with overtly malignant features of Langerhans type cells that express S-100, CD1a and Langerin and show Birbeck granules by ultrastructural examination. They belong to the histiocytic and dendritic cell family which are antigen presenting cells and occur in skin, bone marrow, lymph nodes, spleen, liver, and lung. While the benign form, Langerhans cell histocytosis (LCH) is more common, the malignant form LCS is a rarity. We present a rare case of LCS in a child with lymph node involvement.

Keywords: Langerhans  cell, Malignant, Sarcoma.

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Corresponding Author

Champaka G

Department of Pathology, Kidwai Cancer Institute, Bengaluru, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mob: 08971907498