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Category: Volume 07 Issue 01 January 2019
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Title: Histopathological Spectrum of Spinal Space Occupying Lesions

Authors: Dr S P Tathe, Dr S N Parate, Dr S A Meshram, Dr AA Randale, Dr MA Bhatkule

 DOI: https://dx.doi.org/10.18535/jmscr/v7i1.200

Abstract

Introduction: Spinal space occupying lesions (SOLs) are rare with wide histopathological spectrum. These are categorized based on their location as extradural, intradural and intramedullary. Although the neuroimaging techniques give an idea about precise location and probable diagnosis, histopathology remains the gold standard for the accurate diagnosis of spinal space occupying lesions. The present study was carried out to study the histopathological spectrum, distribution and demographic features of various spinal space occupying lesions.

Materials and Methods: Total 106 cases of spinal space occupying lesions over a period of 3 years [January 2016- December 2018] were studied.

Results:  The most affected age group was 41-60 years with male:female ratio of 1.5:1. Neoplasms formed the majority [83%] of the spinal space occupying lesions. The most common SOL in the intradural compartment was schwannoma and ependymoma in the intramedullary compartment, while tuberculosis was the most common cause of space occupying lesion in extradural compartment.

Conclusion: A location based approach to the spinal SOLs is helpful in establishing an appropriate differential diagnosis. Tissue diagnosis is imperative due to wide spectrum of pathological lesions in this area with differing prognosis and therapeutic protocols.

Keywords: spinal space occupying lesions, extradural, intradural, intramedullary, Histopathologic spectrum.

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Corresponding Author

Dr SN Parate

Department of Pathology, Government Medical College and Superspeciality Hospital, Near Hanuman Nagar Nagpur-440009 Maharashtra, India

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