Title: Magnetic Resonance Spectroscopic Evaluation of Intraaxial Neoplasms
Authors: Dr Subhashree Dash, Dr Braja Behari Panda, Prof Savitri Bhagat, Dr Subhasish Panda
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.195
Abstract
Intraaxial neoplasms constitute a major chunk of intracranial neoplasms. As conventional imaging characteristics are sometimes similar especially when grade of tumor is taken into account, Magnetic Resonance Spectroscopy (MRS) helps in differentiating various neoplasms and their grades. Gliomas are the most commonly encountered neoplasms. Due to delay in diagnosis and/or magnitude of symptoms, usually grade IV gliomas are more prevalent. MRS helps to determine the extent of perilesional spread as well.
A total of 44 patients diagnosed with intraaxial brain neoplasms in conventional MRI were subjected to MRS. Study was done over a period of 2 years. Most common age group of presentation was 51-60yrs of age. Grade IV neoplasms were more frequently encountered.
Diagnostic accuracy of MRS with respect to grading of neoplasms reached 88% as compared to 58% in conventional MRI when 1st differential diagnosis was taken into account.
Keywords: Grade IV glioma, Cho/Cr, Cho/NAA, Lipid lactate, MI/Cr.
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