Title: Plasma Cell Granuloma of Gingiva- A Rare Case Report

Authors: Lt Col (Dr) Manab Kosala, Col (Dr) M Panwar, Dr Jacqueline Jacinta Dias

 DOI: https://dx.doi.org/10.18535/jmscr/v7i1.160

Abstract

Bahadori and Leibow in the year 1973 studied a pulmonary lesion and termed it as “Plasma cell granuloma”. Plasma cell granuloma (PCG) is a rare lesion primarily showing polyclonal plasma cells. Various synonyms of plasma cell granuloma add confusion to the disease terminology, such as atypical gingivostomatitis, idiopathic gingivostomatitis, inflammatory pseudotumor, inflammatory myofibroblastic tumor, histiocytoma, and fibroxanthoma, to mention a few[1,2,3]. It is a rare non-neoplastic lesion and etiopathogenesis of this disease remains unclear. It affects primarily lungs along with some extrapulmonary sites such as the central nervous system, endocrine gland, paranasal sinuses, larynx, lips, tonsils, oral cavity, ears, and orbit. Plasma cell granuloma of gingiva is rarely seen and very few case reports have discussed the same in literature. This case report is a rare case of Plasma cell granuloma of gingiva and highlights the clinical as well as histological findings.[2]

References

  1. Telang A, Telang Oral Plasma cell granuloma: An enigmatic lesion. International Journal of Oral & Maxillofacial Pathology.2013;4(1):64-67.
  2. Imran F, Rajan S, Vijay A case of Plasma Cell Granuloma of an Unknown cause. J Orofac Res.2012;2(4):235-237.
  3. Pettinato G1, Manivel JC, De Rosa N, Dehner Inflammatory myofibr-oblastic tumor (plasma cell granuloma). A clinicopathologic study of 20 cases with immunohistochemical and ultrastructural observations. Am J Clin Pathol. 1990 Nov;94(5):538-46.
  4. Amita K, Vijayshankar S, Anusha K, Hemalatha AL. Diagnostic Dilemma in a Case of Gingival Lesion Plasma Cell Granuloma versus Extramedullary Plasmacytoma- Resolved by Immunohistochemistry: a Case 2015. Int J Med Res Health Sci. 2015;4(2):467-470.
  5. Jeyaraj P, Naresh N, Malik A, Sahoo A rare case of gingival plasma cell granuloma of the gingiva masquerading as a gingival epulis. International Journal of Disease and Disorder. 2013;1(2):16-19.
  6. Pandav AB, Gosavi AV, Lanjewar DN, Jagadale Gingival plasma cell granuloma. Dent Res J 2012;9:816-20.
  7. Phadnaik MB, Attar Gingival plasma cell granuloma. Indian J Dent Res 2010;21:460-2.
  8. Pandav G, Kaur H, Jain S, Pandav Gingival plasma cell granuloma: An enigmatic inflammatory pseudo-tumor with literature review. Int J Contemp Dent Med Rev. 2015;1:1-4
  9. Palaskar S, Koshti S, Maralingannavar M, Bartake Inflammatory myofibroblastic tumor. Contemp Clin Dent 2011;2:274-7.
  10. Reyes E, Zaldivar K & Padilla Plasma cell granuloma in the oral cavity: A case report. J Oral Res 2015; 4(5): 335-339.
  11. Mishra MB, Sharma S, Sharma Plasma Cell Gingivitis: An Occasional Case Report. N Y State Dent J. 2015;81(5):57-60.
  12. Manohar B, Bhuvaneshwari Plasma cell granuloma of gingiva. J Indian Soc Periodontol 2011;15:64-6.

Corresponding Author

Dr. Jacqueline Jacinta Dias

Postgraduate student, Div of Periodontology, Dept of Dental Surgery and Oral Health Sciences, AFMC, Pune

Ph no-9971579012, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.