Title: Study of Various Bacteriological Agents & their Antibiotic Sensitivity Pattern in Surgical Site Infections (SSI)- A Prospective Study

Authors: Dr Laxminarayan Mohanty, Dr Jateen Anshuman

 DOI: https://dx.doi.org/10.18535/jmscr/v7i1.34

Abstract

 

Background & Aim: Surgical site infections cause a significant problem to the surgeons & contribute significantly to the post. op. Morbidity. A lot of organisms starting from staph. aureus, epidermidis, E.coli, klebsiella, pseudomonas, proteus, enterococci are responsible depending on various types of surgical site infections (clean/clean contaminated/contaminated/dirty). Our aim was to study the bacteriological pattern and formulation of a protocol for use of antibiotic according to the sensitivity of organisms in various surgical site infections.

Methods: This prospective study was based on study of various bacteriological agents & their antibiotic sensitivity pattern in 214 patients who were admitted to our surgical unit at S.C.B medical college Cuttack during the period of June 2016 to June 2018 considering the inclusive & exclusive criteria .Among them 29 patients developed surgical site infection (SSI).Post op wound inspection was started on 3rd day, followed by every alternate day. Any secretion or pus if found was sent to dept.of microbiology for culture & sensitivity. Organisms isolated were recorded along with their sensitivity.

Results: In our study of 214 patients among which 29 developed  surgical site infection, Staph. aureous, & epidermidis account  for most of the wound infection in clean wound, E.coli, enterococci, klebsiella, pseudomonas were responsible in clean contaminated , contaminated  & dirty wounds in various proportions

Most of the organisms were sensitive to combination of piperacillin & Tazobactam and Amino glycosides with MRSA (methicillin resistant staph. aureous) were sensitive to linezolide, teicoplanin.

Conclusion: Surgical site infection is a very common nosocomial infection contributing to post operative morbidity. So proper detection of causative agent & their treatment by following their sensitivity pattern decreases the post operative complication as well as reduces the incidence of antibiotic resistance.

Keywords: Surgical site infection, bacteriological agents, sensitivity pattern.

References

  1. Mangram Aj,Horan TC et al:Surgical site infection ,1999.Hospital infection control practices advisory committee. Infect control Hosp epidemiol 20:250-278,1999.
  2. Barie Postsurgical site infections: epidemiology & prevention .Surgery Infect(larchmt)3 (suppl 1):s9-s21,2002.
  3. Yalsin & Baker et al; post op wound infection; Journal of Hosp infections 1995;29:305-309
  4. Tripathy & Raj ;post op wound sepsis; Indian journal of surgery;1984;47:285-288
  5. Cruse PJ,Foord R.The epidemiology of wound infection.A 10 year prospective study of 62939 wounds .Surgical clin North Am. 1980;60(1):27-40
  6. Bochichio GV,Napolitano LM,joshi M,et al;persistent systemic inflammatory responce syndromes predictive of nosocomial infection in trauma. J trauma 53;2002;245-250
  7. Kowli,Nayak,Mehta et al;Hospital infection;Ind journal of surgery;1985;46:475-486
  8. Anvikar,Desmukh,Malik et al ;prospective study of SSI;Indian journal of micro;17;1999;129-32
  9. Condon RE,Wittman DH.The use of antibiotics in gen.surgery.Curr probl Surg 1991;28;801-849
  10. Bratzler DW, Houch PM,Richards C,et al .Use of antibiotic prophylaxis for major surgery ;base line results from the National surgical site infection. prevention project.Arch Surg (140)2005;174-182
  11. Giamarellou H;Treatment options for multidrug resistant bacteria. Expert Rev Anti Infect Ther 4;2006;601-618
  12. Pieracci FM ,barie PS;Intra abdominal infections.Curr Opin Crit Care 13,2007;440-449
  13. Rao AS ,Harsha M;post op wound infections;journal of indian medicines;64;1975;90-93
  14. Morange Saussier V,Giraudeau B,van der Mee N,Quentin R.Nasal carriage of methicillin resistant staphylococcous aureus in vascular surgery.Ann vasc surgery,20; 2006;767-72
  15. Hayashi Y,Paterson DL;stratergies for reduction in duration of antibiotic use in hospitalised patients.clin Inf Dis ,52;2011;1232-1240
  16. Dennesen PJ,Vander ven AJ,Kessel et al;Resolution of infectious parameters after antimicrobial therapy in patients with ventilator associated pnemmonia.Am J Respir Crit Care Med ,163,2001;1371-1375.

Corresponding Author

Dr Laxminarayan Mohanty, Asst. Prof.

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