Title: Assessment of Kidney Function Status in Chickens (Gallus gallusdomestica) in Rural (Elele) and Urban (Nnewi) Areas
Authors: A.N. Okpogba, *E.C. Ogbodo, J.C. Okpogba, R.A Analike, A.K. Amah, B.O. Odeghe, F.N. Ujowundu, V.N. Oguaka, C.E. Onyeneke
DOI: https://dx.doi.org/10.18535/jmscr/v6i12.170
Abstract
Control of accumulation of toxic substances in eco-systems is of great value in the context of global atmospheric pollution. This study investigated the kidney function status of the factory chickens in Nnewi, Anambra State, Nigeria. A total of twenty-nine (29) chicks aged between four (4) and five (5) months were grown to adult birds (chickens) for the study. They were allowed to feed from the surrounding homeland until they were due for the experiment. The chickens were sacrificed to obtain the blood for analyses. Approximately, 5ml of blood sample was collected from the heart into lithium- heparin containers for estimation of biochemical parameters (Na+, K+, Cl-, HCO3-, Urea, and Creatinine). Biochemical parameters were assayed using standard laboratory methods. Thereafter, the data obtained were subjected to statistical analysis by Students t-test using Statistical package for social sciences (SPSS) (Version 16) software and Statistical significance was tested at P<0.05. The result revealed a significant decrease in the mean plasma concentration of HCO3-ion in factory chickens than in control (p<0.05). Furthermore, the result showed that no significant mean differences were observed between all other kidney parameters of the control and factory chickens (p>0.05) respectively, however, while the Na+, K+, and Cl- ions as well as creatinine levels were reduced in the factory chickens, the urea level and urea/creatinine (U/C) ratio was elevated in the factory chickens as against the control. Therefore, this study revealed no deleterious effect on the kidney functions which may be attributed to the short duration of exposure of the factory chickens to the factory sites.
Keywords: Industrialization, kidney functions, factory chickens, Nnewi.
References
- Abdullahi, I.M., Babagana, K. and Yakubu, A.G. (2013). Heavy metals in selected tissues of adult chicken layers (Gallus spp). ARPN Journal of Science and Technology; 3(5):75-79.
- Akan, J.C., Abdulrahman, F.I., Sodipo, O.A. and Chiroma, Y.A. (2010). Distribution of heavy metals in the liver, kidney and meat of beef, mutton, caprine and chicken from KasuwanShanu market in Maiduguri metropolis, Borno State, Nigeria. J. Appl. Sci., Eng. Technol.2(7): 43-748.
- Barbier, O., Jacquillet, G., Tauc, M., Cougnon, M. and Poujeol, P. (2005). Effect of heavy metals on, and handling bythe kidney. Physiol. 99(4): 105-110.
- Choice, D.D. and Richer, G.W. (1974a) Cell proliferation in mouse kidney induced by lead II: synthesis of ribonucleic acid and protein. Invest. 30:652-656.
- Demirezen, O. and Urue, K. (2006). Comparative study of trace elements in certain fish meat and meat products. Food Chemistry. 32: 215-222.
- Dioka, C.E., Orisakwe, O.E., Adeniyi, F.A.A. and Meludu, S.C. (2004). Liver and renal function tests in artisans occupationally exposed to lead in mechanic village in Nnewi, Nigeria. J. Environ. Res. Publ. Health.1(21-25).
- Donald, C., Chuni, L., Sandra, C., Jennifer, A., Regina, K. and Pam, M. (2006). Chemical and biological monitoring o chronic lead poisoning in the rat. Appl. Toxicol. 6(5): 371-776.
- Goodman, D.S. (1985) Nephrotoxicity: Toxic effects in kidneys. In: Williams, P.L. and Burson, J.I. (eds). Industrial toxicology-Safety and Health application in workplace. VanNostrand Reinhold. New York pp106-122.
- Ibeto, C.N. and Okoye, C.O.B. (2010). High levels of heavy metals in blood of the Urban population in Nigeria. J. Environ. Sci; 4(4):371-382.
- Ikem, A. and Egiebor, N.O. (2005) Assessment of trace elements in canned fishes (mackerel, tuna, salmon, sardines and herrings) marketed in Georgia and Alabama (United States of America). Food Composition and Analysis, 18:771–787.
- Kendall, R.J. and Scalon, P.F. (1981). Effect of chronic lead ingestion on reproductive characteristics of ringed turtle doves (Steptopeliarisoria) on tissue lead concentration of adults and their progeny. Poll. 26:203-213.
- Lebedeva, N.V. (1997). Accumulation of heavy metals by birds in the Southwest of Russia. Russian J. Ecol. 28(1): 41-46.
- Mariam, I., Iqbal, S. and Nagra, S.A. (2004). Distribution of some trace and macrominerals in beef, mutton and poultry. J. Agric. Boil. 6(5):816-820.
- Narayanan, S. and Appleton, H. D. (1980) Creatinine: a review. Chem. 26(8):1119-26.
- Niebor, E., Thomassen, Y., Romanova, M., Nikonov, A., Odland, J.O. and Chaschin, V. (2007). Multi-component assessment of worker exposures in a copper refinery: Part 2, Biological exposure indices for copper, nickel and cobalt. Environ. Monit. 9:695-700.
- Ochei, J. and Kolhatkar, J. (2007). Estimation of plasma urea by Berthelot reaction. In:Medical Laboratory Science, Theory and Practice, 6th reprint, Tata McGraw Hill Publishing Company Limited, New Delhi, Pp 114-115.
- Okpogba, A.N., Ogbodo, E.C., Ugwu, E.C., Oguaka, V.N., Dike, C.C. and Ujowundu, F.N. (2018). Comparative assessment of heavy metal levels in chickens (Gallus gallusdomestica) in rural (Elele) and urban (Nnewi) areas. Asian J. Sci. Technol.; 9(11):9056-9059.
- PSR (2013). Physicians for social responsibility; U.S affiliate of International Physicians for the Prevention of Nuclear War, recipient of the 1983 Nobel Price for Peace.
- Sembulingam, K. and Sembulingam, P. (2010). Regulation of acid-base balance by renal mechanism, In:Essentials of Medical Physiology, 5th Edition, Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, Pp44-45.
- Taussky, H.H. (1956). Modified alkaline picrate method determination of creatinine in serum. Chimca. Acta; 1: 200-202.
- Wu, Z., Du, Y., Xue, H., Wu, Y. and Zhou, B. (2012). Aluminum induces neuro-degeneration and its toxicity arises from increased iron accumulation and reactive oxygen species (ROS) production. Aging; 33(1):199-212.