Title: A Case Report of Recurrent Giant Cell Tumor of Distal end Radius

Authors: Dr Anirudh Bansal, Dr Smit Vadher, Dr Arvind Kumar, Dr Sudhir Rawat, Dr Vikramjit Singh

 DOI: https://dx.doi.org/10.18535/jmscr/v6i12.140

Abstract

Introduction

It is a common, locally aggressive benign bone tumour, constituting 5% of all skeletal tumours generally seen in 3rd decade of life with female preponderance. Most common site for GCT is in epiphysio-metaphyseal region with 15% propensity for local recurrence after surgical treatment.GCT of bone is very rarely seen in children and adults older than 65 years of age. GCT occur in approximately one person per million per year. Usually the tumour site is at the long bone meta-epiphysis, especially the distal end radius, femur proximal humerus and tibia.

Giant Cell Tumour (GCT) of bone is benign and locally aggressive tumour. It represents approximately 3% to 5%of all primary tumour. It generally occurs in adults between the age of 20-40 years. We report the case of a distal end radius GCT diagnosed in a 35 year old male. It was treated with radical excision, fibular grafting and dynamic compression plating with K-wire fixation. Wrist was immobilised with above elbow slab. K-wire removed after 6 weeks and wrist mobilisation started.

References

  1. Eckardt, J.J. and Grogan, T.J. (1986) Giant Cell Tumour of Bone. Clinical Orthopaedics and Related Research, 204,45-58.
  2. Dahlin, D.C., Cupps, R.E. and Johnson Jr., E.W. (1970) Giant Cell Tumour: A Study of 195 Cases. Cancer, 25,1061-1070. http://dx.doi.org/10.1002/1097-0142(197005)25:5<1061::AID-CNCR2820250509>3.0.CO;2-E
  3. Goldenberg, R.R., Campbell, C.J. and Bonfiglio, M. (1970) Giant Cell Tumour of Bone: An Analysis Two Hundred and Eighty Cases. Journal of Bone and Joint Surgery, 52, 619-664.
  4. Smith, R.J. and Mankin, H.J. (1977) Allograft Replacement of Distal Radius for Giant Cell Tumor. Journal of Hand Surgery, 2, 299-309. http://dx.doi.org/10.1016/S0363-5023(77)80131-7
  5. Campanacci, M., Baldini, N., Boriani, S. and Sudanese, A. (1987) Giant Cell Tumour of Bone. Journal of Bone and Joint Surgery, 69, 106-114.
  6. Clohisy, D.R. and Mankin, H.J. (1994) Osteoarticular Allograft for Reconstruction after Resection of a Musculoskeletal Tumour in the Proximal End of the Tibia. Journal of Bone and Joint Surgery, 76, 334-349.
  7. Vander Griend, R.A. and Funderburk, C.H. (1993) The Treatment of Giant-Cell Tumours of the Distal Part of the Radius. Journal of Bone and Joint Surgery, 73, 899-908.
  8. Walthar, M. (1911) Resection de extremiteinferieure du radius pour osteosarcoma geffe de I extremitesuperiuete du perone. Sac Chir Par Bull Mem, 37, 739-747.
  9. Campanacci, M. (1976) Giant Cell Tumor and Chondrosarcoma: Grading, Treatment and Results. Recent Results in Cancer Research, 54, 257-261.
  10. Schajowicz, F. (1961) Giant-Cell Tumors of Bone (Osteoclastoma): A Pathological and Histochemical Study. Journal of Bone and Joint Surgery, 43, 1-29.
  11. Szendroi, M. (2004) Giant Cell Tumor of Bone. Journal of Bone and Joint Surgery (British Volume), 86, 5-12.
  12. O’Donnell, R.J., Springfield, D.S., Motwani, H.K., Ready, J.E., Gerhart, M.C. and Mankin, H.J. (1994) Recurrence of Giant Cell Tumours of Long Bones after Curettage and Packing with Cement. Journal of Bone and Joint Surgery (America Volume), 76, 1827-1833.
  13. Cheng, C.Y., Shih, H.N., Hsu, K.Y. and Hsu, R.W. (2001) Treatment of Giant Cell Tumour of the Distal Radius. Clinical Orthopaedics and Related Research, 383, 221-228. http://dx.doi.org/10.1097/00003086-200102000-00026
  14. Vander Griend, R.A. and Funderburk, C.H. (1993) The Treatment of Giant-Cell Tumors of the Distal Part of the Radius. Journal of Bone and Joint Surgery (America Volume), 75, 899-908.
  15. Malawer, M.M. and Dunham, W. (1991) Cryosurgery and Acrylic Cementation as Surgical Adjuncts in the Treatment of Aggressive (Benign) Bone Tumors: Analysis of 25 Patients, 262, 42-57.
  16. Hussain, P. and Singh, V. (2007) Giant Cell Tumor of Distal Radius: A Case Report and Description of Surgical Technique. The Internet Journal of Orthopaedics, 8, Number 2.
  17. Pho, R.W. (1981) Malignant Giant Cell Tumour of Distal End of the Radius Treated by a Free Vascularized Fibular Transplant. Journal of Bone and Joint Surgery (America Volume), 63, 877-884.
  18. Asavamongkolkul, A., Waikakul, S., Phimolsarnti, R. and Kiatisevi, P. (2009) Functional Outcome Following Excision of a Tumour and Reconstruction of Distal Radius. International Orthopaedics, 33, 203-209. http://dx.doi.org/10.1007/s00264-007-0441-7
  19. Deb, H.K. and Das, N.K. (1992) Resection and Reconstructive Surgery in Giant Cell Tumour of Bone. Indian Journal of Orthopaedics, 26, 13-16.

Corresponding Author

Dr Anirudh Bansal

3rd year Resident Doctor, Orthopaedics Department, SBKSMIRC

Sumandeep Vidyapeeth, Vadodara Gujrat, India