Title: Changes in Posterior Corneal Curvature, Asphericity and Longitudinal Spherical Aberrations Following Myopic Laser in Situ Keratomileusis (LASIK)

Authors: Dr Ashok H. Madan, Dr Madhura Chandratreya, Dr Kavita Dhabarde

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i11.112

Abstract

Purpose: To assess the changes in the posterior corneal curvature, asphericity and longitudinal spherical aberrations after myopic laser in situ keratomileusis (LASIK)

Method: Prospective nonrandomized comparative study. 68 eyes of 16 women and 18 men were included, with mean age at the time of surgery of 24.79 +3.47 (range 20-35) years ,with a spherical equivalent(SEQ) of -1.5 to -11.75 (mean ,-5.00 +2.168). All procedures were accomplished with the Star S4 IR excimer laser and the Moria microkeratome. (Flap size 90/130 microns). The residual stromal bed thickness of > 250 um or >50% of original thickness of the cornea was maintained. Subjective refractometry, corneal topographical analysis and pachymetry with Sirius (placido disc topography with Scheimpflug tomography)  were performed before and  3 months after LASIK for myopia (n=12, range -1.5 D to -5.12 D, mean - 3.20+2.10 D ) and myopic astigmatism (n=56, sphere -1.5 to-10.75 D, mean -4.78 + 2.13 D, cylinder -0.25 D to-3.5D, mean -1.07 + 0.78D).

Results: Paired‘t’ test was used for analysis. A P value < 0.05 was considered to be statistically significant. Overall, change of posterior corneal curvature (-6.259+0.18D/-6.27+0.21 D, P=0.10) was not statistically significant. Change of asphericity (0.89+0.25/1.03+0.12, P <0.001) was highly significant. Change in longitudinal spherical aberrations (0.45+0.33/0.61+0.83, P=0.16) was not found to be significant.

Conclusion: No significant change is seen in the Posterior corneal power/ Longitudinal spherical aberrations following LASIK, but change in asphericity of the cornea (from prolate to oblate) is significant.

References

  1. Pallikaris IG, Papatzanaki ME, Stathi EZ, Frenschock O, Georgiadis A. Laser in situ keratomileusis. Lasers Surg Med. 1990;10:463–468.
  2. Dupps WJ Jr. Biomechanical modeling of corneal ectasia.J Refract Surg. 2005;21:186–190.
  3. Seiler T, Koufala K, Richter G. Iatrogenic keratectasia after laser in situ keratomilieusis. J Refract Surg 1998; 14:3 12-7.                             
  4. Seiler T, Quurke A W. Iatrogenic keratectasia after LASIK in a case of forme frustekeratoconus. J Cataract Refract Surg 1998; 24:1007-9.
  5. Probst LE, Machat JJ. Mathematics of laser in situ keratomilieusis for high myopia. J Cataract Refract Surg 1998;24:190-5.
  6. Wang Z, Chen J, Yang B. Posterior corneal surface topographic changes after laser in situ keratomilieusis are related to residual corneal bed thickness. Ophthalmology. 1999;106:406-409.                        
  7. Seitz B, Torres F, Langenbucher A, Behrens A, Suarez E. Posterior Corneal Curvature Changes after Myopic Laser In Situ Keratomilieusis. J Ophthalmol 2001 ;108:666-673.
  8. Azar DT, Koch DD. Laser fundamentals, surgical techniques and complications. Taylor, chapter 2002, 11:163-170.
  9. Khairat Y, Mohamed Y et al. Evaluation of corneal changes after Myopic LASIK using the Pentacam. Clinical 2013:7; 1771-1776.                                                                                             
  10. Bottos KM, Leite MT, Aventura-Isidro M, et al. Corneal asphericity and spherical aberration after refractive surgery. J Cataract Refract Surg. 2011;37:1109–1115 .                                                  
  11. Hou J, Wang Y, Li J, Yang XY, Zhang L. Change of asphericity of posterior corneal surface after refractive surgery. Zhonghua Yan Ke Za Zhi. 2011;47:223–227.
  12. Applegate RA. Limits to vision: can we do better than nature? J Refract Surg. 2000; 16(5): S547-51.
  13. Applegate RA, Howland HC. Refractive surgery, optical aberrations, and visual performance. J Refract Surg. 1997;13:295-299
  14. Guillon M, Lydon DP, Wilson C. Corneal topography: A clinical model. Ophthal Physiol Opt. 1986; 6(1):47-56.
  15. Lam A, Douthwaite W. Measurement of posterior corneal asphericityon Hong Kong Chinese: A pilot study. Ophthal Physiol Opt. 1997;17(4): 348-56.
  16. Kohnen T, Mahmoud K, Buhren J. Comparison of corneal higher-order aberrations induced by myopic and hyperopic LASIK. Ophthalmology .2005 Oct;112(10):1692.                           
  17. Miller JM, Anwaruddin R, et al. Higher order aberrations in normal, dilated, intraocular lens, and laser in situ keratomilieusis corneas. J Refract Surg.2002;18(5):S579-83.

Corresponding Author

Dr Ashok H. Madan

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