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Category: Volume 06 Issue 11 November 2018
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Title: Seroconversion and Prevalence of TTIs (Transfusion Transmissible Infections) among Blood Donors in Southern Part of India

Authors: Kodandarao Kuna, Padmanabham Yalangi, Hemaprakash Pilli, Lakshmipathy Chityala

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i11.90

Abstract

Aims & Objectives: Effective screening of donors blood as per WHO guidelines and to assess the sero prevalence of HIV, HBsAg, HCV, Syphilis and Malaria among population in a locality in southern part of India based on the data of screened donor blood bags.

Material & Methods: During the period from 2012 to Aug 2018, a total number of 17,635 samples from the donated blood bags from a dedicated blood bank in southern part of India are screened for sero infections as per WHO guidelines using Elisa reader and RPR kit. The emphasis is on seroconversion when the tests result positive. The conclusive data is also compared with similar data in other parts of India studied by other eminent authors.

Results & Discussion: It is observed that 297 samples are positive for HBsAg (1.68 %), 68 samples are positive for HIV (0.38 % ), and 59 samples are positive for HCV (0.33 %). Syphilis and Malaria reported not much significant as per Chi-square value. The data on comparision with other similar data showed similar trend except in the large sample study of 2,20,432 where syphilis reported high prevalence.

Conclusion:  Strict quality control, counselling of donars, elimination of paid repeated donors, using the latest time tested gadgets to screen the blood, avoiding contamination, training of blood bank lab technicians at regular intervals updating knowledge, maintaining regular uninterrupted power supply and avoiding resource crunch are very very essential for the best possible quality of blood transfusion.

Keywords:  Blood, donor, seroconversion, prevalence, screening etc.

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Corresponding Author

Padmanabham Yalangi

Associate Professor, Dept. of Microbiology, GIMSR (Gitam Institute of Medical Sciences and Research),

Visakhapatnam, India

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