Title: A Case Report of Neuromyelitis Optica Spectrum Disorders

Authors: Dr R. Guruboo Balaji, Dr S. Noorul Ameen, Prof. D. Rajasekaran

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i11.07

Abstract

Neuromyelitis optica (NMO) and Neuromyelitis optica spectrum disorders (NMOSD) are inflammatory disorders characterized by immune-mediated demyelination and axonal damage predominantly involving optic nerves and spinal cord. Previously NMO was considered as a variant of multiple sclerosis (MS), but now it is considered a separate entity(1). Here we report a case of middle aged female presenting with quadriplegia, urinary retention, sensory abnormalities which suggested myelopathy but without any evidence of optic neuritis, suggesting a diagnosis of  neuromyelitis optica spectrum disorder. The diagnosis was confirmed by positive aquaporin 4 antibody.

References

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  3. The transverse myelitis association overview article- Mealy et al. Epidemiology of neuromyelitis optica in the United states. Arch Neurol. 2012 Jun 25:1-5.doi:10.1001
  4. Wingerchuk DM, Bennett JL, et al. International revised consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology 2015; 85:177.
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Corresponding Author

Dr R. Guruboo Balaji

Post graduate, Department of General Medicine, Chettinad Hospital and Research Institute