Title: Use of filtered vs. Nonfiltered Residual circuit volume, a comparative study

Authors: Mainak De, Kamal Das, Milan Manna, Manisha Halder, Sujoy Poddar, Sudipta Patra

 DOI: https://dx.doi.org/10.18535/jmscr/v6i10.225

Abstract

Cardiac surgery causes large amount of blood loss in form of CPB circuit residual volume. Re infusion of the circuit volume reduces homologous blood requirements and there by eleminats the adverse effects of homologous blood. But unprocessed residual blood retransfusion itself can have tremendous hazards which may lead to increased post op bleeding, Increased homologous blood requirement, SIRS which may ultimately lead to organ dysfunction1. These unwanted effects of unprocessed residual CPB circuit volume can be eliminated by processing it2 as processing by various methods and devices reduce amount of active inflammatory mediators3,4. Due to low cost effectiveness of cell salvage technique we used haemofiltration as a technique to decrease load of activated inflammatory factors5. Our study includes two groups Group A (n=25) who were transfused with unprocessed residual circuit volume and Group B (n=25) who were transfused with residual blood transfused after processing it through haemofiltration. In Group B we observed lower blood and blood product requirement, less bleeding in ist 24 hour post operatively and reduced ventilatorry stay than Group A.

Keywords: Circuit residual volume, haemofiltration, blood loss, Inflammation, autologous blood transfusion

References

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Corresponding Author

Mainak De

3rd yr B.Sc Perfusion Technology, Dept of CTVS, R.G.Kar Medical College, Kolkata