Abstract
Aims: Blood transfusion is a source of transmission of infectious agents to the recipients. With every unit of blood transfused, there is 1% chance of transfusion associated problems including TTIs. The aim of the present study was to study the seroprevalence of HIV, HBV, HCV, syphilis and malaria among the blood donors.
Methodology: The present study was a retrospective study in which a total of 10668 units of donor’s blood were screened for five TTIs from 2013 to 2017 at blood bank, ASCOMS & Hospital, Jammu.
Results: The overall seroprevalence of HIV, HBV, HCV, syphilis and malaria was 0.03%, 0.31%, 0.075%, 0.36% and 0.0% respectively.
Conclusion: All blood donations should be screened for TTIs to ensure safe blood transfusion to the recipients. With the implementation of strict selection criteria of donors and use of sensitive screening tests for TTIs, it is possible to decrease the incidence of TTIs among recipients of blood products.
Keywords: HIV, HBV, HCV, Syphilis, TTIs (Transfusion transmitted infections), Donors.
References
- Arora D, Arora B, Khetarpal A. Seroprevalence of HIV,HBV,HCV and syphilis in blood donors in southern Haryana. Indian J Pathol Microbiol. 2010;53:308-309.
- Chandra T, Kumar A, Gupta A. Prevalence of transfusion transmitted infections in blood donors: An Indian experience. Trop Doct.2009;39:152-154.
- Fernandes H, D’souza PF, D’souza PM.Prevalence of transfusion transmitted infections in voluntary and replacement donors. Indian J Hematol Blood Transfus.2010;26(3):89-91.
- Fiebig EW, Busch MP(2008).Infectious disease screening. In: Technical Manual (16th). American Association of Blood Banks,241-278.
- Garg S, Mathur DR, Garg DK. Comparision of seropositivity of HIV, HBV, HCV and syphilis in replacement and voluntary blood donors in western India. Indian J Pathol Microbiol. 2001;44(4):409-412.
- Gupta N, Kumar V, Kaur A. Seroprevalence of HIV, HBV, HCV and syphilis in voluntary blood donors.Indian J Med Sci.2004;58:255-7.
- Kamran Mohd., Mahmood RT, Khan MA, Mehmood A,Nisar L and Asad MJ. Prevalence of transfusion transmitted infections among blood donors: a prospective study.AJPCT.2014;2(4):540-543.
- Kulkarni N. Analysis of the seroprevalence of HIV,HBV,HCV and syphilitic infections detected in the pretransfusion blood: A short report. International Journal of Blood Transfusion and immunohematology.2012;2:1-3.
- Mujeeb SA,Mehmood K. Prevalence of HBV, HCV and HIV infections among family blood donors. Annals of Saudi Medicine 1996;16(6):702-3.
- Negi G and Gaur DS.Trends of transfusion transmissible diseases among blood donors at Uttarakhand,India. Indian J community Med.2014 Jul-Sep:39(3).
- Pailoor K, Keshav SM,Rai P, D’Cunha O and Lakshmi C.A retrospective study of screening of common transfusion transmitted infections in the blood bank of a tertiary care centre. J. Blood Disorders Transf. 2015,6:2.
- Rao P, Annapurna K.HIV Status of blood donors and patients admitted in KEM Hospital Pune. Indian J Hemat Blood Transf 12:174-176.
- Sabharwal ER, Biswas NK, Purohit V.Prevalence and patterns of transfusion transmissible infections among blood donors in Sri Ganganagar, Rajasthan,India. A retrospective study.J Phar Biomed Sci.2012:15:1-4.
- Sachdeva A, Gupta A, Sharma B, Sharma D, Sharma N. Seroprevalence trends of transfusion transmitted infections among blood donors in a tertiary care hospital of Himachal Pradesh, India. Int J Res Med Sci.2016 Nov;4(11):5002-06.
- Sawke N, Sawke GK, Chawla S. Seroprevalence of common transfusion transmitted infections among Blood Donors. People’s Journal of Scientific Research.2010;3(1).
- Yadav BS, Varma AV, Singh P, Kumar R, Bandi PK. Seroprevalence of Transfusion Infections (TTIs) in blood donors: a study from central India. International Journal of Medical Science and Public Health. 2016;5(6).
Corresponding Author
Swati Arora
ASCOMS, Jammu University, India
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.210
