Title: A Comparative Study of Serum Vitamin D levels in Type 2 Diabetes Mellitus Patients and Age Matched controls

Authors: Balaji.I, N. Paari, S. Balasubramaniyan, C. Subathra, K. Haynes Raja

 DOI: https://dx.doi.org/10.18535/jmscr/v6i10.183

Abstract

Background: Diabetes mellitus is one of the rapidly emerging non-communicable diseases worldwide. This study is done to the assess the vitamin D deficiency existing among the fast growing diabetic population.

Aim: To compare serum vitamin D levels in type 2 diabetes mellitus patients with age matched non diabetic population and to correlate vitamin D levels with the glycemic control and duration of diabetes.

Materials and Methods: This is a hospital based case control study conducted between November 2016 and August 2018. 50 diabetic subjects and 50 age matched non diabetic controls were included in the study. Serum levels of 25(OH)-vitamin D and glycated haemoglobin were measured in both groups.

Results: Mean age group among cases and control were 48.02 ± 9.01 years and 48.20 ± 8.90 years.The mean concentration of vitamin D in the case group was 16.8±7.96ng/dl and in the control group was 21.4±11.8 ng/dl. In diabetic patients, vitamin D level was deficient in 41 (82%), insufficient in 5(10%) and sufficient in 4(8%) patients. In the non diabetic group, these parameters were seen in 33(66%), in 7(14%) and in 10 (20%) respectively. Among diabetic patients, vitamin D level had a significant inverse correlation with patient’s glycated hemoglobin levels.

Conclusion: Vitamin D deficiency was significantly high in diabetic patients than the age matched non diabetic individuals. Also Vitamin D levels were much lower among patients with poor glycemic control.

Keywords: Diabetes mellitus, serum Vitamin D, glycated haemoglobin.

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