Title: A Study on the Prevalence of the Microalbuminuria in non Diabetic, Normotensive Patients with the Acute Myocardial Infarction and to Predict Its Prognostic Significance
Authors: S Ratheesh Anandh, N Chidambaram
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.175
Abstract
Background: The excretion of albumin in urine of 30-300 mg/day is referred to as microalbuminuria, which is not be detected through ordinary urine assessments. The presence of increased Urinary albumin excretion (UAE) signals an growth inside the transcapillary leak rate of albumin and is consequently a marker of micro vascular disorder. Thus, microalbuminuria is an early reaction to myocardial infarction.
Methods: A health facility based totally descriptive study of a hundred patients of acute myocardial infarction became achieved to find the prevalence of microalbuminuria among non-diabetic normotensive individuals of acute Myocardial Infarction; to confirm its prognostic importance of in-hospital complications of the patients admitted; and to set up the correlation of microalbuminuria with cardiac biomarkers.
Results: Microalbuminuria check became positive in 87% patients. The prevalence of microalbuminuria in our study is about 87% and in hospital complications of the acute myocardial infarction patients occur statistically more in patients who are having persistent microalbuminuria on both day 1 and day 5 of urine protein estimation.
Conclusions: Microalbuminuria is more prevalent in patients with acute myocardial infarction patients. Hence, Microalbuminuria is a non specific yet high sensitive marker of myocardial infarction and it could be used as a further biochemical parameter in acute myocardial infarction patients who were non diabetics and can be used as a marker for predicting in-hospital complications
Keywords: Acute myocardial infarction, in-hospital complications, Microalbuminuria
References
- Alvin CP. Diabetes Mellitus. In: Dennis LC, Anthony SF, Dan LL, Eugene B, Stephen LH, Jamenson IL, editors. Harrison's Principles of Internal Medicine. 15 '1' ed. New York, NY: McGraw-Hill; 2001:2109-37.
- Parving HH, Jensen HE, Mogensen CE, Evrin PE. Increased urinary albumin excretion rate in benign essential hypertension. The Lancet. 1974;7868: 1190-2.
- Berton G, Cordiano R, Palmeri R, Cucchni F, De Toni R, Palatini P. Microalbumi-nuria during acute myocardial infarction; a strong predictor for I year mortality. Eur Heart J. 2001;22(16):1466-75.
- Haffner SM, Stein MP, Grubber KK, Hazuda HP, Mitchell BD, Paterson TK. Microalbuminuria: potential marker for increased cardiovascular risk factors in nondiabetic subjects? Arteriosclerosis. 1990;10:727-31.
- David BS. Carbohydrates. In: Burtis AC, Ashwood RE, editors. Tietz Text Book of Clinical Chemistry 3rd ed. Philadelphia: Saunders;1999:798-801.
- Gosling P, Sutcliffe AJ, Cooper MACS, Jones AF. Burn and trauma associated, proteinuria: the role of lipid peroxidation and myoglobin. Annals Clin Biochem. 1988;25:53-9.
- Bilous RW. Diabetes mellitus and the kidneys. In: Warell DA, Cox TM, Firth JD, Edwards BJ, editors. Oxford Text Book of Medicine. 4th edition. New York, NY: Oxford University Press; 2003:374-380.
- Lazzeri, Chiara et al. “Microalbuminuria In Hypertensive Nondiabetic Patients With ST Elevation Myocardial Infarction”. Journal of Cardiovascular Medicine 11.10 (2010): 748-753.
- Khudhair, Safaa Ali. “Microalbuminuria and In- Hospital Complications Of Acute Myocardial Infarction Safaa Ali Khudhair”. Medical Journal of Babylon 10.1 (2013)
- Memon, Abdul Ghaffar and MubashirKolachi. “Relationship OfMicroalbuminurea In Non- Diabetic And Non-Hypertensive Patients With Acute Myocardial Infarction”. Journal of Clinical & Experimental Cardiology 06.09 (2015): n. pag. Web.
- Lekatsas, Ioannis et al. “Prognostic Significance Of Microalbuminuria In Non-Diabetic Patients With Acute Myocardial Infarction”. International Journal of Cardiology 106.2 (2006): 218-223.