Title: A Study of Clinical Profile in Neonatal Seizures with Special Reference to Biochemical Abnormalities at NICU, RMMCH, Chidambaram
Authors: Dr G. Surendiran, Dr S. Ramesh, Dr S. Saravanan, Dr S. Chidambaranathan, Dr Praveen Kumar
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.169
Abstract
Objectives: To study the presentation of seizures in neonate with special reference to clinical etiology and metabolic abnormalities. This study aims to find the etiology, metabolic abnormalities and time of onset in newborn presenting with neonatal seizures in NICU Rajah Muthaih Medical College.
Materials and Methods: This is prospective, observational hospital based study. This study include Hundred neonates, who had seizures within 28 days from birth admitted in Rajah Muthaih Medical College neonatal intensive care unit, were observed for etiological factor, clinical varient and metabolic abnormalities found in neonatal seizure.
Results: The result observed are subtle seizure forms the most common seizure, followed by clonic seizure [focal (25%), multifocal (12.5%). Tonic type of seizure in (7.5%) and myoclonic in (5%). Among metabolic abnormalities hypoglycaemia was found in (22%) and hypocalcaemia in (11%), followed by hyponatremia and hypokalemia Birth asphyxia is the most common cause of seizures, followed by infection and metabolic cause.
Keywords: Neonatal seizure, hypoglycaemia, clonic seizure, Birth asphyxia.
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